Prospective Randomized Controlled Study Comparing Conventional Ventilation Versus A Fully Closed-loop Ventilation (IntelliVent®) In Post Cardiac Surgery ICU Patients

Lellouche, François; Bouchard, Pierre-Alexandre; Wysocki, Marc; Laubscher, Thomas; Novotni, Dominik; Lopez, Rigoberto; Bruehschwein, Frederik; Durish, Geon; L’Her, Erwan

doi:10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6035

Cited by 8 publications

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“…Thus, objectives in terms of PaCO 2 or E T CO 2 and PaO 2 or SpO 2 should be revised to avoid unnecessary over-assistance with potential harmful consequences. The use of closedloop control of ventilation increases the time spent in the desired ventilation zone [19,20] and may help clinicians to revise the objectives. Such closed-loop systems may in theory be able to work with other modes of ventilation, for instance pressure support ventilation (PSV) or volume assist controlled ventilation with closed-loop control of FiO 2 and PEEP.…”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV®) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study

et al. 2012

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Section: Discussionmentioning

confidence: 99%

Safety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV®) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study

et al. 2012

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“…New systems that combine automatic adjustments of ventilator parameters, such as minute ventilation and peak inspiratory pressure, in parallel to automatic adjustment of F IO 2 and PEEP, have recently become available. 40,41 Reports on the use of these systems in adult ventilated patients with acute lung injury and post-cardiac surgery indicate better maintenance of the target ranges of oxygenation and other physiologic targets, less hyperoxemia, and reductions in F IO 2 . These more sophisticated systems also resulted in fewer manual interventions from the clinical team to adjust the ventilator settings.…”

Section: In the Adultmentioning

confidence: 99%

Automated Closed Loop Control of Inspired Oxygen Concentration

Claure

Bancalari

2012

Respir Care

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Oxygen therapy is extensively used in premature infants and adults with respiratory insufficiency. In the premature infant the goal during manual control of the F IO 2 is to maintain adequate oxygenation and to minimize the exposure to hypoxemia, hyperoxemia, and oxygen. However, this is frequently not achieved during routine care, which increases the risks of associated side effects affecting the eye, lungs, and central nervous system. In the adult the primary goal is to avoid hypoxemia, but conventional methods of oxygen supplementation may fall short during periods of increased demand. On the other hand, there are growing concerns related to unnecessarily high F IO 2 levels that increase the exposure to hyperoxemia and excessive oxygen use in settings where resources are limited. Systems for automated closed loop control of F IO 2 have been developed for use in neonates and adults. This paper will give an overview of the rationale for the development of these systems, present the evidence, and discuss important advantages and limitations.

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“…Automated mechanical ventilation systems are another way to help implement protective ventilation. In a preliminary study, we evaluated the new Intellivent system (Hamilton medical, Bonaduz, Switzerland) in patients after cardiac surgery [ 115 ]. We showed that VTs were automatically reduced below 10 mL/kg of PBW after a few minutes of mechanical ventilation, and the respiratory rate was automatically increased to maintain a stable minute ventilation.…”

Section: Challenges and Controversy To The Use Of Protective Ventimentioning

confidence: 99%

Low Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome: A Paradigm Shift in Mechanical Ventilation

Lipes

Bojmehrani

Lellouche

2012

Critical Care Research and Practice

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Protective ventilation with low tidal volume has been shown to reduce morbidity and mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Low tidal volume ventilation is associated with particular clinical challenges and is therefore often underutilized as a therapeutic option in clinical practice. Despite some potential difficulties, data have been published examining the application of protective ventilation in patients without lung injury. We will briefly review the physiologic rationale for low tidal volume ventilation and explore the current evidence for protective ventilation in patients without lung injury. In addition, we will explore some of the potential reasons for its underuse and provide strategies to overcome some of the associated clinical challenges.

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Prospective Randomized Controlled Study Comparing Conventional Ventilation Versus A Fully Closed-loop Ventilation (IntelliVent®) In Post Cardiac Surgery ICU Patients

Cited by 8 publications

References 0 publications

Safety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV®) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study

Safety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV®) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study

Automated Closed Loop Control of Inspired Oxygen Concentration

Low Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome: A Paradigm Shift in Mechanical Ventilation

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