Prospective Randomized Controlled Trial Comparing the Effects of Noncontact Low-Frequency Ultrasound with Standard Care in Healing Split-Thickness Donor Sites

Current perspectives on therapeutic ultrasound in the management of chronic wounds: a review of evidence

“…In the author's experience with NCLFU dating back to original unpublished studies (Conner-Kerr et al, 35 presented in 2003 at the Symposium on Advanced Wound Care) performed using the initial prototype for the MIST ® therapy device, infected, acute porcine wounds healed 30% faster than control, infected wounds. A prospective, randomized controlled trial conducted by Prather et al 36 examining the effects of 40 kHz NCLFU plus standard of care (SOC) therapy versus SOC therapy revealed significantly faster rates of healing in patients with split thickness donor sites. The mean time to healing was 12.1 days in the NCLFU plus SOC versus 21.3 days in the SOC therapy-only group.…”

Randomized clinical trial of autologous skin cell suspension for accelerating re-epithelialization of split-thickness donor sites

“…A wide variety of novel wound dressings have been proposed for donor‐site management. There is evidence that hydrocolloid dressings facilitate fastest healing and minimal patient discomfort. However, despite optimal conditions, donor‐site re‐epithelialization may typically take 7–21 days.…”

Immediate Regrafting of the Split Thickness Skin Graft Donor Site Assists Healing

“…These range from vendor manufactured materials [e.g., Xeroform (Covidien, Mansfield, Mass.) or Kaltostat (Convatec, Skillman, N.J.)], 3–8 innovative approaches (cultured epithelial grafts, 2 noncontact low-frequency ultrasound 9 ), or even the peculiar (aluminum foil, banana leaves, a free flap). 10–12 Donor-site location may be just as important a factor, as it is well known that the scalp has an accelerated healing time due to the number of epidermal appendages present that promote reepithelialization.…”