Prospective Randomized Study Comparing Ex-PRESS to Trabeculectomy

Abstract

There was no statistically significant difference between the trabeculectomy and Ex-PRESS groups regarding IOP, success rates, complications, additional interventions, and bleb morphology.

Comparison of trabeculectomy versus Ex-PRESS: 3-year follow-up

“…Dahan et al 8 randomised fellow eyes of 15 patients and after a mean follow-up of 23.6 months reported better success rates with the Ex-PRESS implant, although there was no difference in mean intraocular pressure (IOP). The other two studies found no difference in success rates between Ex-PRESS and trabeculectomy, with follow-up periods of 1 and 2 years, respectively 2 6…”

“…Three-year follow-up data of subjects enrolled in our 1-year prospective RCT comparing Ex-PRESS with trabeculectomy were obtained 2. Charts were reviewed retrospectively for missed data if the study visit had passed and prospectively to obtain 2-year and 3-year results.…”

“…There are presently six published clinical trials comparing Ex-PRESS with trabeculectomy (table 1);2 6–10 however, only four are prospective randomised controlled trials (RCTs) 2 6–8. The first by De Jong et al 7 initially reported better success rates with Ex-PRESS, however after 3 years of follow-up, there was no longer a statistically significant difference.…”

“…Given the conflicting long-term results of published RCTs, we extended our previously published RCT2 to compare the 3-year outcomes of Ex-PRESS versus trabeculectomy.…”

A Review of the Ahmed Glaucoma Valve Implant and Comparison with Other Surgical Operations

“…EXP was developed in an effort to make filtration surgery more straightforward. Nonetheless, it seems that the efficacy and safety profile of the EXP are not superior to standard trabeculectomy [44][45][46][47]. Only a few studies directly comparing AGV and EXP have been published.…”