Purpose
To investigate the efficacy of a novel respiratory motion scheme, where only the center of k-space is gated using respiratory navigators, versus a fully respiratory-gated acquisition for 3D flow imaging.
Methods
3D flow images were acquired axially using a GRE sequence in a volume covering the ascending and descending aorta, and the pulmonary artery bifurcation in 12 healthy subjects (33.2±15.8 years; 5 men). For respiratory motion compensation, two gating & tracking strategies were used with a 7mm gating window: 1) All of k-space acquired within the gating window (fully-gated), 2) Central k-space acquired within the gating window, and the remainder of k-space acquired without any gating (center-gated). Each scan was repeated twice. Stroke volume, mean flow, peak velocity and signal-to-noise-ratio measurements were performed both on the ascending and the descending aorta for all acquisitions, which were compared using a linear mixed-effects model and Bland-Altman analysis.
Results
There were no statistical differences between the fully-gated and center-gated strategies for the quantification of stroke volume, peak velocity and mean flow, as well as the signal-to-noise-ratio measurements. Furthermore, the proposed center-gated strategy had significantly shorter acquisition time compared to the fully-gated strategy (13:19±3:02 vs. 19:35±5:02, P<0.001).
Conclusions
The proposed novel center-gated strategy for 3D flow MRI allows for markedly shorter acquisition time without any systematic variation in quantitative flow measurements in this small group of healthy volunteers.