“…In addition, periconceptional Zn deficiency has been associated with abnormalities in early embryonic growth in rats and mice (Hurley and Shrader, 1975;Peters et al, 1991) and karyotypic changes in severely Zn-deficient rats (Bell et al, 1975). Zn supplementation has been suggested to reduce pregnancy complications and improve fetal growth and pregnancy out¬ come in women (Jameson, 1976;McMichael et al, 1982; Cherry et Simmer et al, 1990) and typically managed sheep (Egan, 1972;Masters and Fels, 1980;Masters and Moir, 1983 (Hunt et al, 1984;Ghosh et al, 1985;Hunt et al, 1985;Austen et al, 1989;Mahomed et al, 1989;Apgar, 1992 (Thurmond et al, 1990b Thurmond and Picanso (1990). Period of risk for abortion was defined as gestational days (Thurmond and Picanso, 1990 (Keen and Feldman, 1987).…”