Prospective study of alcoholism treatment

Vaillant, George E.; Clark, William D.; Cyrus, Catherine; Milofsky, Eva S.; Kopp, Jeffrey B.; Wulsin, Victoria Wells; Mogielnicki, Nancy P.

doi:10.1016/0002-9343(83)90349-2

Cited by 119 publications

(25 citation statements)

References 35 publications

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“…69 A 5-year abstinence is the gold standard, but it exceeds the boundary of survival for patients who have stopped drinking after diagnosis of ALD. 55,56 Verrill et al noted that abstinence during the first 30 days following the diagnosis of cirrhosis appeared to be an excellent predictor of abstinence at a mean period of 3.4 years follow-up and was associated with a 7-year survival of 72% (vs 44% survival of patients continuing to drink). 70 From an ethical standpoint, one should question whether factors associated with relapse rates should influence the decision regarding transplantation, as do other criteria, such as age, presence of young children, or ability to strictly follow the treatment designed to prevent rejection.…”

Section: Discussionmentioning

confidence: 99%

“…54 Indeed, Vaillant has demonstrated that after maintaining abstinence for as long as 2 years, approximately 40% of patients with alcohol dependence relapse, although subsequent relapse becomes unlikely after 5 years of abstinence. 55,56 De Gottardi et al followed up with 387 patients (23.8% women) who underwent LTX for alcoholic cirrhosis over 15 years (between 1989 and 2005 in Geneva, Switzerland and Lyon, France) to identify factors that could be associated with the recurrence of harmful alcohol consumption following LTX. 48 Harmful drinking was defined by a declared alcohol consumption level 440 g/d associated with the presence of alcohol-related damage, either mental or physical (e.g., histologic features of alcoholic liver injury seen on liver biopsy specimens).…”

Section: Relapse After Ltx In Aldmentioning

confidence: 99%

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Risk Factors for Alcohol Relapse Following Orthotopic Liver Transplantation: A Systematic Review

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Section: Relapse After Ltx In Aldmentioning

confidence: 99%

Risk Factors for Alcohol Relapse Following Orthotopic Liver Transplantation: A Systematic Review

et al. 2015

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“…Treatment for AUD has traditionally focused on abstinence from alcohol as the most acceptable outcome. Yet, pioneering work in the latter half of the 20th century examined "resumed normal drinking" (Davies, 1962), "controlled drinking" (Sobell & Sobell, 1976, 1978Vaillant et al, 1983), "non-problem drinking" (Polich et al, 1980), and "social drinking" (Nordström & Berglund, 1987;Öjehagen et al, 1994) outcomes among individuals in alcohol treatment programs. Early research also considered a variety of drinking goals (Pattison, 1976), including social drinking goals, as potential outcomes (Öjehagen & Berglund, 1989).…”

mentioning

confidence: 99%

How Much Is Too Much? Patterns of Drinking During Alcohol Treatment and Associations With Post-Treatment Outcomes Across Three Alcohol Clinical Trials

Witkiewitz

Roos

Pearson

et al. 2017

J. Stud. Alcohol Drugs

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ABSTRACT. Objective:This secondary data analysis examined patterns of drinking during alcohol treatment and associated drinking outcomes during the first year following treatment. The goal was to provide clinicians with guidance on which patients may be most at risk for negative long-term outcomes based on drinking patterns during treatment. Method: This study was an analysis of existing data (N = 3,851) from three randomized clinical trials for alcohol use disorder: the COMBINE Study (n = 1,383), Project MATCH (n = 1,726), and the United Kingdom Alcohol Treatment Trial (n = 742). Indicators of abstinence, non-heavy drinking, and heavy drinking (defined as 4/5 or more drinks per day for women/men) were examined during each week of treatment using repeated-measures latent class analysis. Associations between drinking patterns during treatment and drinking intensity, drinking consequences, and physical and mental health 12 months following intake were examined. Results: Seven drinking patterns were identified. Patients who engaged in persistent heavy drinking throughout treatment and those who returned to persistent heavy drinking during treatment had the worst long-term outcomes. Patients who engaged in some heavy drinking during treatment had better long-term outcomes than persistent heavy drinkers. Patients who reported low-risk drinking or abstinence had the best long-term outcomes. There were no differences in outcomes between low-risk drinkers and abstainers. Conclusions: Abstinence, low-risk drinking, or even some heavy drinking during treatment are associated with the best long-term outcomes. Patients who are engaging in persistent heavy drinking are likely to have the worst outcomes and may require a higher level of care. (J. Stud. Alcohol Drugs, 78, 59-69, 2017)

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“…12), or were completed more than 30 years ago (13). Even fewer studies were based on behavioural theories, rather than diagnostic criteria, which change over time (14,15). The modern understanding of treatment effect encompasses a broad concept of rehabilitation at a level of psychosocial functioning (16).…”

Section: Introductionmentioning

confidence: 99%

A temporal profile of pro-abstinence-oriented constructs from the modified theory of planed behavior in a Slovenian clinical sample of treated alcoholics – an 18-year follow-up

Radovanović¹,

Rus-Makovec²

2018

Slovenian Journal of Public Health

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Original scientific articleIntroduction: Using the modified Theory of Planned Behaviour (mTPB), different indicators of therapeutic success were studied to understand pro-abstinence behavioural orientation during an 18-year after-care period following a 3-month intensive alcoholism treatment. The indicators were: perceived needs satisfaction (NS), normative differential (ND), perceived alcohol utility (UT), beliefs about treatment programme benefits (BE) and behavioural intentions (BI). Methods:The sample of 167 patients who consecutively started an intensive alcoholism treatment programme has been followed-up for 18 years, using standardised ailed instruments at the end of the treatment, and in the years 4-5, 9 and 18 of follow-up. The last data collection was completed by 32 subjects in 2010. The analysis followed the standard explore-analyse-explore approach. After the initial descriptive exploration of data, multivariate analysis of variance (MANOVA) in SPSS statistical package was set to explore between-groups and within-groups differences over time.Results: At the between-group level, BI remained stable at the same level as at the end of the treatment programme, whereas BE and UT robustly changed over time and levelled off after 10 years of follow-up. NS and ND show a trend of pro-abstinent orientation and level off after 10 years of follow-up, although the trend is not significant. The same results were confirmed by the within-subject level. Conclusions:Studied constructs stabilised after ten years of follow-up, apart from BI. The latter suggests that BI level needed for completion of an intensive treatment programme suffices for the maintenance of abstinence when accompanied by the change in perception of alcohol usefulness. Radovanović M, Rus-Makovec M. A temporal profile of pro-abstinence-oriented constructs from the modified theory of planed behavior in a Slovenian clinical sample of treated alcoholics -an 18-year follow-up. Uvod: Z uporabo konstruktov iz prilagojene Teorije načrtovanega vedenja smo raziskovali kazalnike terapevtskega uspeha po intenzivnem zdravljenju sindroma odvisnosti od alkohola in v obdobju

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Prospective study of alcoholism treatment

Cited by 119 publications

References 35 publications

Risk Factors for Alcohol Relapse Following Orthotopic Liver Transplantation: A Systematic Review

Risk Factors for Alcohol Relapse Following Orthotopic Liver Transplantation: A Systematic Review

How Much Is Too Much? Patterns of Drinking During Alcohol Treatment and Associations With Post-Treatment Outcomes Across Three Alcohol Clinical Trials

A temporal profile of pro-abstinence-oriented constructs from the modified theory of planed behavior in a Slovenian clinical sample of treated alcoholics – an 18-year follow-up

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