Prospective study of Centurion® versus Infiniti® phacoemulsification systems: surgical and visual outcomes

Oh, Lawrence; Nguyen, Chu Luan; Wong, Eugene; Wang, Samuel Sherng Young; Francis, Ian C.

doi:10.18240/ijo.2017.11.10

Cited by 8 publications

(14 citation statements)

References 17 publications

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“…concluded that AFS improved the efficiency of phacoemulsification and saved the cumulative dissipated energy (CDE), but Malik and colleagues reported that no significant difference existed in CDE between the two systems with the same phaco tip [ 13 , 15 , 16 ]. Also, results are not entirely consistent across studies, with the conservation of CDE associated with AFS varied from 13.5% to 40% [ 13 , 15 , 17 , 18 ]. However, most studies are conducted on different phacoemulsifiers, which might cause potential bias and reduce the credibility of the results [ 14 , 15 , 17 ].…”

Section: Introductionmentioning

confidence: 93%

“…Also, results are not entirely consistent across studies, with the conservation of CDE associated with AFS varied from 13.5% to 40% [ 13 , 15 , 17 , 18 ]. However, most studies are conducted on different phacoemulsifiers, which might cause potential bias and reduce the credibility of the results [ 14 , 15 , 17 ]. A similar situation occurs in the reports on other surgical outcomes such as corneal endothelial cells, postoperative IOP and the retinal vasculature [ 18–20 ].…”

Section: Introductionmentioning

confidence: 93%

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A prospective randomized clinical trial of active-fluidics versus gravity-fluidics system in phacoemulsification for age-related cataract (AGSPC)

Luo

Chen

et al. 2022

Annals of Medicine

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Background To figure out the efficacy, effects, safety and patient’s subjective perceptions of phacoemulsification with the active-fluidics system (AFS). Patients and methods This was a prospective, randomized, double-masked, controlled clinical study. Age-related cataract patients were recruited and randomly assigned to the AFS group and gravity-fluidics system (GFS) group in a ratio of 1:1 to have phacoemulsification. Participants were followed up at one day, one week, one month and three months postoperatively (Chinese Clinical Trial Registry, ChiCTR2100044409). Results The overall included participants were 107 finally. The total aspiration time of the AFS group was significantly less than that of the GFS group ( p = .020), while no significant difference existed in cumulative dissipated energy and estimated fluid usage between the two groups. The best corrected visual acuity was significantly better in the AFS group at one day and one week postoperatively ( p = .002, p = .038 respectively). The recovery of central corneal thickening and macular superficial vasculature increase was earlier in the AFS group. The central retinal thickness was significantly higher in the GFS group at one month and three months postoperatively ( p = .029, p = .016 respectively). The incidence of corneal adverse events was higher in GFS group ( p = .035). No serious adverse events occurred in either group. Pain scores and the scores of Cat-PROM5 questionnaire of the AFS group were significantly lower than that of the GFS group ( p = .011, p = .002 respectively). Conclusion AFS improves the efficiency, effects, safety and patients’ subjective perceptions of phacoemulsification compared with GFS. It is worthwhile to promote its application in cataract surgery. KEY MESSAGES The active-fluidics system automatically detects and maintains stable intraocular pressure at the set value. The active-fluidics system improves the efficiency, effects, safety and patients’ subjective perceptions in phacoemulsification.

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Section: Introductionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 93%

A prospective randomized clinical trial of active-fluidics versus gravity-fluidics system in phacoemulsification for age-related cataract (AGSPC)

Luo

Chen

et al. 2022

Annals of Medicine

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“…The active-fluidics system has been put into use for many years, but it is not yet widespread 15 21 32. Most of the researches on it are laboratory studies, or focusing on intraoperative parameters; there are few studies on the results and injuries of the surgery 12 16 18 33. In order to fully evaluate changes caused by the active-fluidics system in phacoemulsification, more items need to be taken into account.…”

Section: Discussionmentioning

confidence: 99%

Active-fluidics versus gravity-fluidics system in phacoemulsification for age-related cataract (AGSPC): study protocol for a prospective, randomised, double-blind, controlled clinical trial

Luo

Chen

et al. 2022

BMJ Open

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IntroductionThe active-fluidics system is a new irrigation system of phacoemulsification that automatically detects and maintains stable intraocular pressure at the set value. This trial is designed to compare the efficacy, visual outcomes, safety and patients’ subjective perceptions of cataract surgery with the active-fluidics system and gravity-fluidics system.Methods and analysisThis trial will recruit 110 patients with age-related cataract at the Chinese People’s Liberation Army (PLA) General Hospital (Beijing, China) and they will be randomly assigned to the active-fluidics group and gravity-fluidics group in a ratio of 1:1 to have phacoemulsification. Patients will be followed up at 1 day, 1 week, 1 month and 3 months postoperatively. The primary outcomes are the cumulative dissipated energy and best corrected visual acuity. Secondary outcomes include: estimated fluid usage, U/S time, total aspiration time, intraocular pressure, corneal endothelium parameters, retinal thickness, macular superficial vessel density, pain scores, scores of the Cataract surgery Patient-Reported Outcome Measures Questionnaire and the complication rates. The data will be independently analysed by the statistical team, who will be masked for the allocation information as participants are.Ethics and disseminationThis study was approved by the Ethics Committee of Chinese PLA General Hospital (approval no. S2021-068-01). Informed consent will be obtained from each participant. All the results will be published in peer-reviewed journals and used for scholarly communication or technical guidance. Protocol version 1.0.Trial registration numberChinese Clinical Trial Registry (ChiCTR2100044409).

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“…[629] A recent study by Oh et al comparing active-fluidics phacoemulsification system with gravity-based system found that there was a statistically significant difference between them, with active-fluidics offering better surgical and visual outcomes. [30] Moreover, in higher nuclear grades of cataracts (3 and more), visual outcomes were superior with the active-fluidics system. [30] Studies have also reported comparable surgical complications in higher nuclear densities.…”

Section: Discussionmentioning

confidence: 99%

“…[30] Moreover, in higher nuclear grades of cataracts (3 and more), visual outcomes were superior with the active-fluidics system. [30] Studies have also reported comparable surgical complications in higher nuclear densities. [63132] An animal study had showed that the amount of “chatter” was lesser with the active-fluidics technology, and it was recommended that lesser torsional power may be required than gravity-based systems.…”

Section: Discussionmentioning

confidence: 99%

Active-fluidics-based torsional phacoemulsification in diabetic eyes: A prospective interventional study

Khokhar

Sen

Dhull

2019

Indian J Ophthalmol

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Purpose: To compare the outcomes of active-fluidics based torsional phacoemulsification in diabetics and nondiabetics using a balanced tip. Methods: Two hundred and forty-eight patients undergoing senile cataract surgery using torsional phacoemulsification on an active-fluidics-based platform from December 2016 to August 2017 were included in this prospective, nonrandomized, interventional cohort study; of the 248 patients, 54 were controlled diabetics and 194 were nondiabetics. Intraoperative parameters such as cumulative dissipated energy (CDE), total ultrasound time, torsion usage time, torsion amplitude, aspiration time, and fluid usage were documented and compared. Endothelial cell loss (ECL) and central corneal thickness (CCT) were evaluated at 1 month postoperatively. Results: Diabetics and nondiabetics did not differ in CDE, total ultrasound time, torsion amplitude, aspiration time, fluid usage, endothelial cell count, and CCT. ECL on Day 1 (10.2 ± 8.0%) and Day 30 (11.05 ± 8.3%) were significantly higher in diabetics ( P = 0.025 and P = 0.045, respectively). There was an increase in CCT on Day 1 ( P = 0.018), which settled by Day 30. Grade 4 cataracts in diabetics had significantly higher CCT at Day 1 ( P = 0.032) and Day 30 ( P = 0.007). In the diabetic subgroup, Grades 3 and 4 cataracts required lower CDE ( P < 0.001) and Grade 4 cataracts showed higher ECL than others till 1 month of follow-up ( P < 0.05). Conclusion: Intraoperative and postoperative parameters after torsional phacoemulsification are comparable in diabetics and nondiabetics. Endothelial changes and pachymetry may be related to the grade of cataract in diabetics.

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Prospective study of Centurion® versus Infiniti® phacoemulsification systems: surgical and visual outcomes

Abstract: CDE is 28.87% less, and VOs are significantly improved, in denser cataracts in the CPS compared with the IPS. The authors recommend the CPS for cases with denser nuclei.

Cited by 8 publications

References 17 publications

A prospective randomized clinical trial of active-fluidics versus gravity-fluidics system in phacoemulsification for age-related cataract (AGSPC)

A prospective randomized clinical trial of active-fluidics versus gravity-fluidics system in phacoemulsification for age-related cataract (AGSPC)

Active-fluidics versus gravity-fluidics system in phacoemulsification for age-related cataract (AGSPC): study protocol for a prospective, randomised, double-blind, controlled clinical trial

Active-fluidics-based torsional phacoemulsification in diabetic eyes: A prospective interventional study

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