Prospective study of loss of health-related quality adjusted life years in children and their families due to uncomplicated and hospitalised varicella

Marlow, Robin; Gouveia, Catarina; Correia, Paula; Brett, Ana; Silva, Catarina; Gameiro, Inês; Rua, Inês; Dias, João Carlos Pinto; Martins, Marta Fonseca; Diogo, Rui; Lopes, Teresa da Silva; Hipólito, Elsa; Moreira, Diana; Alves, Manuela Costa; Prata, Filipa; Labrusco, Miguel; Gomes, Susana; Fernandes, Alexandre Rodrigo Mendes; Andrade, Alexandra; Morais, Catarina Granjo; Virtuoso, Maria João; Zarcos, Maria Manuel; Raposo, Ana Teresa; Boon, Adam; Finn, Adam

doi:10.1016/j.vaccine.2022.12.011

Cited by 4 publications

(1 citation statement)

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“…In most cases the disease is mild, although serious complications can occur, more commonly in adults particularly pregnant women and in immunocompromised individuals. Other complications occurring at an estimated rate of 2-6% (Rodrigues et al, 2023) include secondary bacterial infections of the skin or soft tissues. Recent chickenpox infection is an important risk factor for invasive Group A streptococcus (iGAS) in children (Zangarini et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

UK healthcare professionals’ attitudes towards the introduction of varicella vaccine into the routine childhood vaccination schedule and their preferences for delivery

Sherman,

Allerton-Price,

Lingley-Heath

et al. 2023

Preprint

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BackgroundVaricella (chickenpox) is a highly contagious disease caused by the varicella-zoster virus. Although typically a mild disease, varicella can cause complications leading to severe illness and even death. Safe and effective varicella vaccines are available. The Joint Committee on Vaccination and Immunisation is planning to review the evidence regarding the introduction of varicella vaccine into the UK’s routine childhood immunisation schedule.ObjectivesTo explore UK healthcare professionals’ (HCPs) knowledge and attitudes towards varicella vaccination, its introduction to the UK routine childhood immunisation schedule, and their preferences for how it should be delivered.DesignWe conducted an online cross-sectional survey exploring HCPs’ attitudes towards varicella, varicella vaccine, and their preferences for delivery of the vaccine between August and September 2022.Participants91 HCPs working in the UK (96.7% female, 3.3% male, mean age 48.7 years).ResultsGeneral vaccine attitudes in this group were very positive. Gaps in knowledge about varicella were revealed: 21.0% of respondents disagreed or were unsure that chickenpox can cause serious complications, while 41.8% were unsure or did not believe chickenpox was serious enough to vaccinate against. After receiving some basic information about chickenpox and the vaccine, almost half of the HCPs (47.3%) in our survey would prefer to administer the varicella vaccine combined with MMR.ConclusionsGiven the positive influence of HCPs on parents’ decisions to vaccinate their children, it is important to understand HCPs’ views regarding the introduction of varicella vaccine into the routine schedule. Our findings highlighted areas for training and HCPs’ preferences which will have implications for policy and practice should the vaccine be introduced.

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Section: Introductionmentioning

confidence: 99%