Prospective Trial of Water Vapor Thermal Therapy for Treatment of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia in Subjects with a Large Prostate: 6- and 12-month Outcomes

Woo, Henry; Levin, Richard; Cantrill, Christopher; Zhou, Shaw; Neff, Donald; Sutton, Mark; Bailen, James; Darson, Michael; Horgan, John; Zantek, Paul; Marty-Roix, Robyn

doi:10.1016/j.euros.2023.10.006

Cited by 3 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This indicates that even patients with PV > 80 cc can achieve lasting benefits from WVTT beyond the period studied in short-term studies. 29,30 However, caution is encouraged in extrapolating our findings to guide treatment for patients with PV sizes at the extremes. In our sample, most patients in the < 30 cc and > 80 cc cohorts have PVs near the respective cutoffs.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Water Vapor Thermal Therapy Outcomes Across a Broad Range of Prostate Volumes

Hawks-Ladds,

Tawfik,

Babar

et al. 2024

Urology Practice

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Long-Term Water Vapor Thermal Therapy Outcomes Across a Broad Range of Prostate Volumes

Hawks-Ladds,

Tawfik,

Babar

et al. 2024

Urology Practice

View full text Add to dashboard Cite

Real-world experience of water vapour therapy (Rezum) in patients with benign prostatic enlargement: a retrospective single-center study

Wolters,

Krastel,

Winkler

et al. 2024

Prostate Cancer Prostatic Dis

View full text Add to dashboard Cite

Background Water vapor thermal therapy (Rezum) is a minimally invasive treatment for benign prostatic enlargement (BPE). Studies reporting urodynamic results regarding the procedure are rare. Our study aimed to assess the effectiveness of Rezum on urinary outcome parameters in a consecutive series of patients and compare urodynamic data before and after treatment. Methods We retrospectively evaluated all the patients treated with Rezum between 07/2017 and 12/2023 at our institution. Patients who had more than one Rezum intervention, those who were unable to void (i.e., catheter-dependent patients), and those with insufficient data were excluded from the data analysis. Descriptive outcomes, such as symptom scores (IPSS, IPSS-QoL), peak flow in uroflowmetry (Qmax), post-micturition residual urine volume (PVR), and prostate volume (PVol), were analyzed. If available, preoperative and postoperative urodynamic results were evaluated. Results In total, 250 Rezum procedures were performed during the observational period. After applying the exclusion criteria, the data from 193 patients were included in the analysis. Patients achieved significant symptom relief as measured using the IPSS (46% reduction) and IPSS-QoL scores (41% reduction). Qmax improved by 4.8 ml/s, as the mean PVR significantly decreased by 50%. PVol and PSA values decreased by 30% and 27.5%, respectively. In 19/193 patients with a urodynamic evaluation, pre- and postoperative data analysis showed a significant reduction in the bladder outlet obstruction index (BOOI) by approximately 70%. Conclusions Rezum is effective and can improve urinary symptoms. In appropriate patients, Rezum can significantly reduce the bladder outlet obstruction (BOO).

show abstract

Real-World experience of water vapour therapy (Rezum) in patients with benign prostatic enlargement: a retrospective single-center study

Wolters,

Krastel,

Winkler

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Water vapor thermal therapy (Rezum) is a minimally invasive treatment for benign prostatic enlargement (BPE). Studies reporting urodynamic results regarding the procedure are rare. Our study aimed to assess the effectiveness of Rezum on urinary outcome parameters in a consecutive series of patients and compare urodynamic data before and after treatment.Methods We retrospectively evaluated all the patients treated with Rezum between 07/2017 and 12/2023 at our institution. Patients who had more than one Rezum intervention, those who were unable to void (i.e., catheter-dependent patients), and those with insufficient data were excluded from the data analysis. Descriptive outcomes, such as symptom scores (IPSS, IPSS-QoL), peak flow in uroflowmetry (Qmax), post-micturition residual urine volume (PVR), and prostate volume (PVol), were analyzed. If available, preoperative and postoperative urodynamic results were evaluated.Results In total, 250 Rezum procedures were performed during the observational period. After applying the exclusion criteria, the data from 193 patients were included in the analysis. Patients achieved significant symptom relief as measured using the IPSS (46% reduction) and IPSS-QoL scores (41% reduction). Qmax improved by 4.8 ml/s, as the mean PVR significantly decreased by 50%. PVol and PSA values decreased by 30% and 27.5%, respectively. In 19/193 patients with a urodynamic evaluation, pre- and postoperative data analysis showed a significant reduction in the bladder outlet obstruction index (BOOI) by approximately 70%.Conclusions Rezum is effective and can improve urinary symptoms. In appropriate patients, Rezum can significantly reduce the bladder outlet obstruction (BOO).

show abstract

Prospective Trial of Water Vapor Thermal Therapy for Treatment of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia in Subjects with a Large Prostate: 6- and 12-month Outcomes

Cited by 3 publications

References 23 publications

Long-Term Water Vapor Thermal Therapy Outcomes Across a Broad Range of Prostate Volumes

Long-Term Water Vapor Thermal Therapy Outcomes Across a Broad Range of Prostate Volumes

Real-world experience of water vapour therapy (Rezum) in patients with benign prostatic enlargement: a retrospective single-center study

Real-World experience of water vapour therapy (Rezum) in patients with benign prostatic enlargement: a retrospective single-center study

Contact Info

Product

Resources

About