Prospective value of self-report and performance-based tests of functional status for 18-month outcomes in elderly patients

Nikolaus, Thorsten; Bach, Matthias; Oster, P.; Schlierf, G.

doi:10.1007/bf03339578

Cited by 39 publications

(28 citation statements)

References 24 publications

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“…However, the cross‐sectional design of the present study did not allow us to determine whether the measured handgrip strength differed from habitual strength or if the handgrip was impaired as a result of the presenting condition (see limitations in the succeeding texts). Our results partially confirm those of previous studies that analyzed the prospective association between customary handgrip strength and hospital admission, which showed varying results The Hertfordshire Cohort Study provided evidence that handgrip strength among community‐dwelling men and women in the UK was associated with risk of hospital admission over the following decade. In contrast, a prospective study of 279 older adults aged ≥70 years from Germany who were followed up for 18 months found no association between handgrip strength and the risk of hospital admission .…”

Section: Discussionsupporting

confidence: 88%

Reference values for handgrip strength and their association with intrinsic capacity domains among older adults

Ramírez‐Vélez

Correa-Bautista

García-Hermoso

et al. 2019

J cachexia sarcopenia muscle

100

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Objective The purposes of this study were three‐fold: (i) to describe handgrip strength in older individuals aged ≥60 years in Colombia; (ii) to identify sex‐specific and age‐specific muscle weakness cut‐off points in older adults; and (iii) to determine the odds of adverse events for each of the intrinsic capacity domains for individuals with handgrip strength greater than the muscle weakness cut‐off points, as compared with their weaker counterparts. Methods A cross‐sectional study was conducted in Colombia, among 5237 older adults aged ≥60 years old (58.5% women, 70.5 ± 7.8 years), according to ‘SABE Survey 2015’. Handgrip strength data were obtained with a Takei dynamometer. Sociodemographic variables, five domains of intrinsic capacity (i.e. locomotion, vitality, cognition, psychological, and sensory), and medical conditions were assessed and analyzed. Adjustments variables were age, ethnicity, socio‐economic status, urbanicity, body mass index, smoking status, alcohol intake, drug use, physical activity, and co‐morbid chronic diseases. Sex‐stratified analyses were conducted with logistic regression models. Results Handgrip strength was greater among men than among women (26.7 ± 8.5 vs. 16.7 ± 5.7 kg, respectively, P < 0.001) at all ages. Weak handgrip strength cut‐off points ranged from 17.4 to 8.6 and from 10.1 to 4.9 in men and women, respectively. Overall, participants with optimal handgrip strength had better intrinsic capacity [in men, odds ratio (OR) = 0.62, 95% confidence interval (CI) 0.53 to 0.71; P < 0.001; and in women, OR = 0.79, 95% CI 0.68 to 0.92; P = 0.002] than their weaker counterparts. Also, men with optimal handgrip strength had a lower risk of hospitalization (OR = 0.47, 95% CI 0.29 to 0.78; P = 0.004) than their weaker counterparts. Conclusions This study is the first to describe handgrip strength values and cut‐off points for muscle weakness among a nationally representative sample of Colombian older adults by age and sex. After categorizing older adults as weak or not weak based on the handgrip cut‐off points, non‐weakness was associated with a decreased odds of intrinsic capacity impairments. These cut‐off points may be good candidates for clinical assessment of risks to physical and mental health in older Colombian adults.

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Section: Discussionsupporting

confidence: 88%

Reference values for handgrip strength and their association with intrinsic capacity domains among older adults

Ramírez‐Vélez

Correa-Bautista

García-Hermoso

et al. 2019

J cachexia sarcopenia muscle

100

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“…5, 13-14 In the few studies that examined the relationship between TUG and other outcomes, TUG was found to predict ADL disability 4, 10 and nursing home admission. 15 …”

Section: Introductionmentioning

confidence: 99%

Is Timed Up and Go Better Than Gait Speed in Predicting Health, Function, and Falls in Older Adults?

Viccaro

Perera

Studenski

2011

Journal of the American Geriatrics Society

378

301

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OBJECTIVES While gait speed (GS) predicts many outcomes in older adults, Timed Up and Go (TUG) is recommended for clinical assessment of mobility and fall risk. The two measures are rarely compared. We assessed whether TUG is superior to GS in predicting multiple geriatric outcomes. DESIGN Prospective cohort study. SETTING Medicare health maintenance organization and Veterans’ Affairs primary care clinics. PARTICIPANTS Adults aged 65 years and older (N = 457). MEASUREMENTS Baseline GS and TUG were used to predict health decline by EuroQol and SF-36 global health; functional decline by NHIS ADL score and SF-36 physical function index; hospitalization; and single and recurrent falls over 1 year. RESULTS Mean age was 74 years and 44% were female. Odds ratios for all outcomes were equivalent for GS and TUG. Using area under the ROC curve ≥ 0.7 for acceptable predictive ability, GS and TUG each alone predicted decline in global health, new ADL difficulty, and falls, with no difference in predictive ability between performance measures. Neither performance measure predicted hospitalization, EuroQol decline, or physical function decline. As continuous variables, TUG did not add predictive ability to GS for any outcome. CONCLUSION GS predicts most geriatric outcomes, including falls, as does the TUG. The time alone in TUG may not add to information provided by GS, although its qualitative elements may have other utility.

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“…The timed 'up and go' test (TUG) may discriminate between those individuals with better home independence, lower risk of falling and reduced mortality [8][9][10] . Moreover, TUG may be useful for the assessment of balance and physical mobility in seniors.…”

Section: Introductionmentioning

confidence: 99%

Walking for the Assessment of Balance in Healthy Subjects Older than 40 Years

Spagnuolo

Jürgensen²,

Iwama³

et al. 2010

Gerontology

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Background: The Berg scale and the timed ‘up and go’ test (TUG) are established measures to assess mobility in frail older adults. As an alternative to self-paced tests to assess aerobic exercise capacity, the incremental shuttle walk test (ISWT) was developed. We hypothesized that ISWT may be useful for the assessment of aerobic capacity and balance simultaneously in healthy adults. Objectives: There are 3 objectives: (1) to evaluate the intra-tester reliability of TUG in healthy subjects; (2) to compare the validity of TUG, ISWT and comfortable gait speed (GS) to evaluate balance assessed by the Berg balance scale, and (3) to evaluate the correlations among these walking tests. Methods: We studied a sample of 64 subjects (82.81% women) aged 40–84 years to assess the intra-tester reliability of TUG. Of these, 21 subjects also performed ISWT, GS and the Berg balance scale. We also assessed height, weight, body mass index, spirometry and reported physical activity. Results: The average time to complete TUG was 7.23 ± 1.27 s. The interclass correlation coefficient of TUG was excellent (0.936; 95% CI: 0.895–0.961). Age (r = 0.36), GS (r = –0.64), GS/height (r = –0.44), ISWT (r = –0.65) and the Berg score (r = –0.65) were correlated with TUG (p < 0.05). The Berg score was significantly (p < 0.05) correlated with GS (r = 0.61) and ISWT (r = 0.61). Moreover, ISWT was mutually related with GS (r = 0.68). We evaluated 2 models of linear regression, using GS and TUG as independent variables in each of them. In the 1st model, GS described 47% of the ISWT variability. In the 2nd, TUG described 42.7% of the ISWT variability. Conclusions: The capacity of walking is related to balance in healthy adults and seniors. Our results suggest the usefulness of ISWT as a new tool for the simultaneous evaluation of the aerobic capacity and balance in healthy subjects. An important part of the ISWT variation was explained by GS and TUG. Secondly, we confirmed the significant influence of age in the TUG performance and the excellent reliability of this field walking test.

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Prospective value of self-report and performance-based tests of functional status for 18-month outcomes in elderly patients

Cited by 39 publications

References 24 publications

Reference values for handgrip strength and their association with intrinsic capacity domains among older adults

Reference values for handgrip strength and their association with intrinsic capacity domains among older adults

Is Timed Up and Go Better Than Gait Speed in Predicting Health, Function, and Falls in Older Adults?

Walking for the Assessment of Balance in Healthy Subjects Older than 40 Years

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