Prospectively Randomized Comparison of Different Mechanical Aortic Valves

Autschbach, Rüdiger; Walther, Thomas; Falk, Volkmar; Kostelka, Martin; Rösler, Annegret; Langebartels, Georg; Krüger, Melanie; Diegeler, Anno; Mohr, Friedrich W.

doi:10.1161/01.cir.102.suppl_3.iii-1

Cited by 62 publications

(25 citation statements)

References 16 publications

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“…In reports about short-term [14], medium-term [15,16,17] and long-term [13,18,19,20] experiences, the Carbomedics prosthetic heart valve has proven to be a highly reliable device with no structural failures and a low incidence of valve-related complications which results in a low over-all mortality. Comparative studies of different mechanical aortic valves demonstrated no clinically relevant differences among the tested bileaflet valves [21,22]. Most common complications associated with an implanted bileaflet prosthesis are valve thrombosis, embolism, anticoagulant-related bleeding, paravalvular leakage and prosthetic valve endocarditis.…”

Section: Discussionmentioning

confidence: 95%

Complete detachment of an aortic valve prosthesis 10 years after implantation

Grubwieser

Pavlic

Hoefer

et al. 2003

International Journal of Legal Medicine

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A 47-year-old male patient died unexpectedly 10 years after replacement of the aortic valve with a Carbomedics heart valve prosthesis required for post-endocarditic valve stenosis. The man was in regular medical attendance by his general practitioner and in hospital. Clinical data and examinations did not suggest the reoccurrence of endocarditis. Three months before his death a haemolytic anaemia of unknown genesis was diagnosed. One afternoon, while lifting a heavy object, the man suffered acute chest pain and collapsed. Resuscitation failed and the patient died in hospital. Autopsy revealed the completely detached valve prosthesis within the ascending aorta. Histological examination confirmed a chronic endocarditis at the site of the valve implantation.

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Section: Discussionmentioning

confidence: 95%

Complete detachment of an aortic valve prosthesis 10 years after implantation

Grubwieser

Pavlic

Hoefer

et al. 2003

International Journal of Legal Medicine

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“…Whether the design variations of the newer valves make a difference in clinical outcomes is uncertain. In one study that prospectively randomized 300 valve operations to receive ATS, Carbomedics, and St. Jude HP, there was no difference in early outcomes in terms of operative mortality or valve related complications [14]. Similarly, in a 1-year comparison of 52 patients who were randomly assigned to receive the On-X versus the Top Hat valve, there was no difference in clinical outcomes of thromboembolic or hemorrhagic events [15].…”

Section: Mechanical Valve Choicesmentioning

confidence: 99%

Heart valve replacement: Which valve for which patient?

Huh

Bakaeen²

2006

Curr Cardiol Rep

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The ideal heart valve substitute would show no deterioration or thrombogenicity, offer no resistance to blood flow, and be easy to implant. However, such a valve does not exist and we must accept compromises in some of these qualities based on our patients' needs. In selection of cardiac valve prosthesis, valve-related factors such as durability, thrombogenicity, and fluid dynamics should be carefully matched to patient-related factors such as age, size, life expectancy, comorbidities, plans for pregnancy, and lifestyle. In addition, surgeon- or operation-related factors should be considered. Technical aspects of implantation, ease of reoperation, and operative mortalities may tip the risk and benefit balance in a particular direction. We review currently available heart valve prostheses and the clinical factors that are involved in selection of a heart valve substitute.

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“…Austschbach et al [1] compared in a randomized trial different mechanical aortic prostheses. They randomized 300 patients to receive an ATS (ATS Medical, Minneapolis, MN), Carbomedics (Sulzer Carbomedics, Austin, TX), or St. Jude (St. Jude Medical, Sylmar, CA) prosthesis.…”

Section: How To Choose a Valvular Prosthesismentioning

confidence: 99%

Recent clinical trials in valvular heart diseases

Enríquez-Sarano

2002

Curr Cardiol Rep

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Prospectively Randomized Comparison of Different Mechanical Aortic Valves

Cited by 62 publications

References 16 publications

Complete detachment of an aortic valve prosthesis 10 years after implantation

Complete detachment of an aortic valve prosthesis 10 years after implantation

Heart valve replacement: Which valve for which patient?

Recent clinical trials in valvular heart diseases

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