Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review

Mounika, Addanki; Ilangovan, Bhaargavi; Mandal, Sushmita; Yashwant, Waghaye Shraddha; Gali, Swetha Priya; Shanmugam, Akalya

doi:10.1016/j.ultsonch.2022.106121

Cited by 13 publications

(6 citation statements)

References 179 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ultrasonic‐assisted extraction has been shown to be an effective method for improving the yield of antioxidants from C. gileadensis compared to the HDE method. This is because the ultrasonic energy helps break down the plant material's cell walls, which increases the availability of antioxidants for extraction (Mounika et al, 2022 ). However, the amount of antioxidants obtained through ultrasonic‐assisted extraction depends on extraction parameters such as ultrasonic energy duration, frequency, and intensity, as well as the type and amount of solvent used.…”

Section: Resultsmentioning

confidence: 99%

“…Ultrasonic-assisted extraction has been shown to be an effective method for improving the yield of antioxidants from C. gileadensis compared to the HDE method. This is because the ultrasonic energy helps break down the plant material's cell walls, which increases the availability of antioxidants for extraction (Mounika et al, 2022). the plant material into the solvent, leading to a greater yield of antioxidants compared to HDE method (Dash et al, 2021;Khadhraoui et al, 2021).…”

Section: Antioxidant Activity Using (Dpph) Radical Scavengingmentioning

confidence: 99%

See 1 more Smart Citation

Antioxidant activity and total phenolic compounds of Commiphora gileadensis extracts obtained by ultrasonic‐assisted extraction, with monitoring antiaging and cytotoxicity activities

Ahmed

Rashed²,

Almoiliqy

et al. 2023

Food Science & Nutrition

View full text Add to dashboard Cite

Commiphora gileadensis (C. gileadensis) has been identified and linked with various health benefits and pharmaceutical potential for its phytochemical activities and chemical constituents. This study aimed to evaluate ultrasonic‐assisted extraction (USE) technique for total phenols content from C. gileadensis leaf compared to the hydrodistillation extraction (HDE). Our results showed that the USE operating conditions were identified as: MeOH·H2O solvent‐to‐fresh sample ratio of 80:20 (v/v); ultrasonic power/frequency at 150 W/20 kHz; and a temperature of 40 ± 1°C; subjected to acoustic waves intermittently for a calculated time (5 min) during the total programmed time of 12 min. The USE exhibited (118.71 ± 0.009 mg GAE/g DM) more amounts of all phenols than HDE (101.47 ± 0.005 mg GAE/g DM), and antioxidant (77.78 ± 0.73%, 75.27 ± 0.59% scavenging inhibition of DPPH), respectively. Anti‐aging and Cytotoxicity activities were investigated. The results of biological evaluations showed that the crude extracts of C. gileadensis significantly extended the replicative lifespan of K6001 yeast. In addition, in vitro cytotoxicity against the HepG2 cell line showed significant anticancer activity, and approximately 100 μg/mL is required to decrease viability compared with that of the control. This study is proven for a larger scale to extract and isolate compounds of C. gileadensis for potential utilization in the pharmaceutical industry. In conclusion, advanced methods afford an extract with high activity in the biological properties of the extract.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Antioxidant Activity Using (Dpph) Radical Scavengingmentioning

confidence: 99%

Antioxidant activity and total phenolic compounds of Commiphora gileadensis extracts obtained by ultrasonic‐assisted extraction, with monitoring antiaging and cytotoxicity activities

Ahmed

Rashed²,

Almoiliqy

et al. 2023

Food Science & Nutrition

View full text Add to dashboard Cite

show abstract

“…Furthermore, HFPs contain many active ingredients, and their reactions are complex 9,10 . In addition, the chemical structures of HFP components may change depending on the method used to extract them, making it even more difficult to predict interactions accurately 11,12 …”

Section: Introductionmentioning

confidence: 99%

“…9,10 In addition, the chemical structures of HFP components may change depending on the method used to extract them, making it even more difficult to predict interactions accurately. 11,12 Studies on drugs for which there is a wealth of information suggest that some interactions involve enzymes that metabolize the drug. 13,14 Although the interactions between some drugs and their metabolizing enzymes have already been well studied, those between HFPs and their metabolizing enzymes have rarely been studied.…”

mentioning

confidence: 99%

Development of method using language processing techniques for extracting information on drug–health food product interactions

Yoshizaki,

Kuriya,

Yamamoto

et al. 2024

Brit J Clinical Pharma

View full text Add to dashboard Cite

AimsHealth food products (HFPs) are foods and products related to maintaining and promoting health. HFPs may sometimes cause unforeseen adverse health effects by interacting with drugs. Considering the importance of information on the interactions between HFPs and drugs, this study aimed to establish a workflow to extract information on Drug‐HFP Interactions (DHIs) from open resources.MethodsFirst, Information on drugs, enzymes, their interactions, and known DHIs was collected from multiple public databases and literature sources. Next, a network consisted of enzymes, HFP, and drugs was constructed, assuming enzymes as candidates for hubs in Drug‐HFP interactions (Method 1). Furthermore, we developed methods to analyze the biomedical context of each drug and HFP to predict potential DHIs out of the DHIs obtained in Method 1 by applying BioWordVec, a widely used biomedical terminology quantifier (Method 2‐1 and 2‐2).Results44,965 DHIs (30% known) were identified in Method 1, including 38 metabolic enzymes, 157 HFPs, and 1256 drugs. Method 2‐1 selected 7401 DHIs (17% known) from the DHIs of Method 1, while Method 2‐2 chose 2819 DHIs (30% known). Based on the different assumptions in these methods where Method 2‐1 specifically selects HFPs interacting with specific enzymes and Method 2‐2 specifically selects HFPs with similar function with drugs, the propsed methods resulted in extracting a wide variety of DHIs.ConclusionsBy integrating the results of language processing techniques with those of the network analysis, a workflow to efficiently extract unknown and known DHIs was constructed.

show abstract

“…Non-invasive biomedical benefits of ultrasound-assisted extraction of compounds from various food sources is reviewed and critically discussed by Mounika et al . [8] The review provides a comprehensive description of several bioactive compounds that can be extracted from different natural sources (propoli, pomegranate and orange peels, grape skins, mango pomace, raspberries, purple basil etc) using ultrasound with high efficacy and various biomedical properties (cardiovascular, anti-diabetic, antiobesity antioxidant anti-cancer and antimicrobial properties). On this note, Shokri et al [9] have reported on the effect of ultrasound on the physical and chemical properties of milk proteins.…”

mentioning

confidence: 99%

Special issue on “Ultrasound-assisted engineering of materials for biomedical uses”

Besford

Cavalieri

2022

Ultrasonics Sonochemistry

View full text Add to dashboard Cite

Prospects of ultrasonically extracted food bioactives in the field of non-invasive biomedical applications – A review

Cited by 13 publications

References 179 publications

Antioxidant activity and total phenolic compounds of Commiphora gileadensis extracts obtained by ultrasonic‐assisted extraction, with monitoring antiaging and cytotoxicity activities

Antioxidant activity and total phenolic compounds of Commiphora gileadensis extracts obtained by ultrasonic‐assisted extraction, with monitoring antiaging and cytotoxicity activities

Development of method using language processing techniques for extracting information on drug–health food product interactions

Special issue on “Ultrasound-assisted engineering of materials for biomedical uses”

Contact Info

Product

Resources

About