Prostate cancer arising in ectopic prostatic tissue within the left seminal vesicle: a rare case diagnosed with multi-parametric magnetic resonance imaging and magnetic resonance imaging-transrectal ultrasound fusion biopsy

Abstract

BackgroundBenign ectopia of prostatic glandular tissue in the seminal vesicles is rare with only three prior cases reported in the literature. Prostate cancer, arising within prostatic ectopia in the seminal vesicles, has never been described and therefore presents a challenge in both diagnosis and management.Case presentationHerein, we report a rare case of prostatic adenocarcinoma in ectopic prostate tissue in the left seminal vesicle, without evidence of prostatic glandular involvement. This case was diagnosed on multi-parametric magnetic resonance imaging and confirmed with magnetic resonance imaging-transrectal ultrasound fusion biopsy.ConclusionsAwareness of this unusual phenomenon is significant because of the potential occurrence of malignancy to arise in unexpected, extra-glandular locations, which are not routinely sampled on routine transrectal ultrasound biopsy. However attention to lesions with characteristic multi-parametric magnetic resonance imaging features of prostate cancer, regardless of extra-glandular location, will help direct tissue sampling, facilitate a timely diagnosis and ensure appropriate management.

Giant retrovesical ectopic prostatic adenoma. Case report and revision of the literature

“…Ectopic prostate is an unusual finding in the genitourinary tract; most aberrant prostatic tissue occurs in the urethra and urinary bladder but has also been observed in the testis, epididymis, bowel, cervix, and seminal vesicle. 1 These findings suggest that embryonic prostatic tissue can migrate outside the urinary tract and reach a size that is large enough to cause problems in the majority of the cases but makes it difficult to detect in the early stages. Ectopic prostatic tissue has histological and immunohistochemical characteristics that are indistinguishable from those of normal prostatic tissue and most likely represent the persistence of embryonic structures; rarely is ectopic benign prostatic tissue accompanied by primary protate cancer.…”

Ectopic prostatic tissue in the perineum

“…14 Furthermore, a report of ectopic prostate cancer (Gleason 4+3=7) in the seminal vesicles surrounded by normal prostatic glands with a transrectal prostate biopsy showing no intraprostatic cancer was managed with radiotherapy and hormonal treatment. 15 Ectopic prostatic tissue is a rare entity but significant as it may be a site for primary prostate cancer and will cause a persistently raised PSA following a radical prostatectomy.…”

Erratum to: prostate cancer arising in ectopic prostatic tissue within the left seminal vesicle: a rare case diagnosed with multi-parametric magnetic resonance imaging and magnetic resonance imaging-transrectal ultrasound fusion biopsy

“…Unfortunately, the original version of this article [ 1 ] contained an error. The spelling of the author “Atif Zaheer” was misspelt “Atif K. Zaheer”.…”