Prostate Cancer Screening at National Cancer Institute Comprehensive and Clinical Cancer Centers

Taylor, Kathryn L.; Africano, Nicole L.; Schwartz, Marc D.; Cullen, Jennifer; Ahaghotu, Chiledum

doi:10.1093/jnci/djh073

Cited by 2 publications

(1 citation statement)

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“…200 Las células madre leucémicas pueden mantenerse en esos nichos evitando la muerte por agentes quimioterápicos. 201 Los mecanismos de protección inducida por el estroma son múltiples y están interrelacionados, implicando una serie de citocinas, quimiocinas y moléculas de adhesión, que pueden aumentar las proteínas antiapoptóticas. 202,203 El stroma-secreted median la migración, implantación y movilización de las células hemopoyéticas, lo que 204-207 La unión de 208 que está mediado intracelularmente por las vías de ERK y PI3K.…”

Section: Interacciones De La Célula Blástica Con El Estromaunclassified

Nuevas estrategias terapéuticas en leucemias agudas mieloblásticas: evaluación preclínica de la eficacia y el mecanismo de ación

Colado¹

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Section: Interacciones De La Célula Blástica Con El Estromaunclassified

Nuevas estrategias terapéuticas en leucemias agudas mieloblásticas: evaluación preclínica de la eficacia y el mecanismo de ación

Colado¹

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Lack of Comprehension of Common Prostate Cancer Terms in an Underserved Population

Kilbridge

Fraser

Krahn

et al. 2009

JCO

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A B S T R A C T PurposeTo assess the comprehension of common medical terms used in prostate cancer in patient education materials to obtain informed consent, and to measure outcomes after prostate cancer treatment. We address this issue among underserved, African-American men because of the increased cancer incidence and mortality observed in this population. Patients and MethodsWe reviewed patient education materials and prostate-specific quality-of-life instruments to identify technical terms describing sexual, urinary, and bowel function. Understanding of these terms was assessed in face-to-face interviews of 105, mostly African-American men, age Ն 40, from two low-income clinics. Comprehension was evaluated using semiqualitative methods coded by two independent investigators. Demographics were collected and literacy was measured. ResultsFewer than 50% of patients understood the terms "erection" or "impotent." Only 5% of patients understood the term "incontinence" and 25% understood the term "bowel habits." More patients recognized word roots than related terms or compound words (eg, "rectum" v "rectal urgency," "intercourse" v "vaginal intercourse"). Comprehension of terms from all domains was statistically significantly correlated with reading level (P Ͻ .001). Median literacy level was fourth to sixth grade. Prostate cancer knowledge was poor. Many patients had difficulty locating key anatomic structures. ConclusionLimited comprehension of prostate cancer terms and low literacy create barriers to obtaining informed consent for treatment and to measuring prostate cancer outcomes accurately in our study population. In addition, the level of prostate cancer knowledge was poor. These results highlight the need for prostate cancer education efforts and outcomes measurements that consider literacy and use nonmedical language.

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Prostate Cancer Screening at National Cancer Institute Comprehensive and Clinical Cancer Centers

Cited by 2 publications

References 3 publications

Nuevas estrategias terapéuticas en leucemias agudas mieloblásticas: evaluación preclínica de la eficacia y el mecanismo de ación

Nuevas estrategias terapéuticas en leucemias agudas mieloblásticas: evaluación preclínica de la eficacia y el mecanismo de ación

Lack of Comprehension of Common Prostate Cancer Terms in an Underserved Population

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