Prostate-specific health-related quality of life and patient-physician communication — A 3.5-year follow-up

Ernstmann, Nicole; Herden, Jan; Weißbach, L.; Karger, André; Hower, Kira Isabel

doi:10.1016/j.pec.2019.07.030

Cited by 7 publications

(10 citation statements)

References 62 publications

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“…Patient-centered communication represents a critical step toward alleviating therapeutic burden [ 19 ]. The importance of prompt and frequent updates to the history of onset and/or exacerbation of symptoms and the changes in on-treatment versus baseline activity levels should be highlighted during physician training.…”

Section: Discussionmentioning

confidence: 99%

“…Patient-centered communication is particularly important when developing a care plan: allaying fears, managing pain, and adverse treatment effects, as well as the timely referral to hospice for end-of-life care [ 18 ]. Patient-centered communication with HCPs has been associated with better health-related quality of life (HRQoL) [ 19 ], emphasizing the importance of open, bidirectional dialog.…”

Section: Factors Defining Therapeutic Burdenmentioning

confidence: 99%

See 1 more Smart Citation

Treating the patient and not just the cancer: therapeutic burden in prostate cancer

Spratt

Shore

Sartor

et al. 2021

Prostate Cancer Prostatic Dis

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Background Prostate cancer (PC) is a leading cause of death in older men. Androgen deprivation therapy (ADT) is considered the standard-of-care for men with locally advanced disease. However, continuous androgen ablation is associated with acute and long-term adverse effects and most patients will eventually develop castration-resistant PC (CRPC). The recent approval of three, second-generation androgen receptor inhibitors (ARIs), apalutamide, enzalutamide, and darolutamide, has transformed the treatment landscape of PC. Treatment with these second-generation ARIs have produced positive trends in metastasis-free survival, progression-free survival, and overall survival. For patients with non-metastatic CRPC, who are mainly asymptomatic from their disease, maintaining quality of life is a major objective when prescribing therapy. Polypharmacy for age-related comorbidities also is common in this population and may increase the potential for drug–drug interactions (DDIs). Method This review summarizes the multiple factors that may contribute to the therapeutic burden of patients with CRPC, including the interplay between age, comorbidities, concomitant medications, the use of ARIs, and financial distress. Conclusions As the treatment landscape in PC continues to rapidly evolve, consideration must be given to the balance between therapeutic benefits and potential treatment-emergent adverse events that may be further complicated by DDIs with concomitant medications. Patient-centered communication is a crucial aspect of alleviating this burden, and healthcare professionals (HCPs) may benefit from training in effective patient communication. HCPs should closely and frequently monitor patient treatment responses, in order to better understand symptom onset and exacerbation. Patients also should be encouraged to participate in exercise programs, and health information and support groups, which may assist them in preventing or mitigating certain determinants of the therapeutic burden associated with PC and its management.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Factors Defining Therapeutic Burdenmentioning

confidence: 99%

Treating the patient and not just the cancer: therapeutic burden in prostate cancer

Spratt

Shore

Sartor

et al. 2021

Prostate Cancer Prostatic Dis

View full text Add to dashboard Cite

show abstract

“…This explanation may also apply to the association between worse EPIC scores and poorer ratings of the quality of help received. A third explanation for our findings could be that the surgeons’ communication skills were not good enough [ 24 ]. They may not have been fully able to capture when patients need help, or to present adverse effects in a way that was understood by the patient.…”

Section: Discussionmentioning

confidence: 99%

Experience Measures after Radical Prostatectomy: A Register-Based Study Evaluating the Association between Patient-Reported Symptoms and Quality of Information

et al. 2022

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Patient-reported data are important for quality assurance and improvement. Our main aim was to investigate the association between patient-reported symptoms among patients undergoing radical prostatectomy and their perceived quality of information before treatment. In this single-centre study, 235 men treated with robotic-assisted radical prostatectomy (RARP) between August 2017 and June 2019, responded to a follow-up questionnaire 20–42 months after surgery. A logistic regression analysis was performed to assess the association between patient-reported symptoms, measured with Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP), and the perceived quality of information. Adverse effects were defined as a higher EPIC score at follow-up than at baseline. The majority (77%) rated the general information as good. Higher EPIC-CP at follow-up was significantly associated with lower perceived quality of information, also after adjustment for age and level of education (bivariate model OR 1.12, 95% CI 1.07; 1.16, p < 0.001 and multiple model OR 1.12 95% CI 1.08; 1.17, p < 0.001). The share who rated information as good was almost identical among those who reported more symptoms after treatment and those who reported less symptoms (78.3% and 79.2%). Consequently, adverse effects could not explain the results. Our findings suggest a need for improvement of preoperative communication.

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“…To assess the severity of UI the ICIQ-SF total scores (questions 1-3) were recoded into four levels of incontinence: slight (1-5), moderate (6-12), severe (13)(14)(15)(16)(17)(18), and very severe (19)(20)(21). 11 The erectile function (EF) was assessed using the International Index of Erectile Function (IIEF) questionnaire.…”

Section: Prosmentioning

confidence: 99%

“…11 The erectile function (EF) was assessed using the International Index of Erectile Function (IIEF) questionnaire. 12 The answers from the erectile function domain of the IIEF (IIEF-EF) resulted in a score between 1-30 and were categorized as: no ED (26-30), mild ED (22)(23)(24)(25), mild to moderate ED (17)(18)(19)(20)(21), moderate ED (11)(12)(13)(14)(15)(16)) and severe ED (1-10). 12…”

Section: Prosmentioning

confidence: 99%

Patient-reported outcome measures compared to clinician reported outcomes regarding incontinence and erectile dysfunction in localized prostate carcinoma after robot assisted radical prostatectomy: Impact on management

Tillier,

Boekhout,

Veerman

et al. 2023

Urologic Oncology: Seminars and Original Investigations

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Prostate-specific health-related quality of life and patient-physician communication — A 3.5-year follow-up

Cited by 7 publications

References 62 publications

Treating the patient and not just the cancer: therapeutic burden in prostate cancer

Treating the patient and not just the cancer: therapeutic burden in prostate cancer

Experience Measures after Radical Prostatectomy: A Register-Based Study Evaluating the Association between Patient-Reported Symptoms and Quality of Information

Patient-reported outcome measures compared to clinician reported outcomes regarding incontinence and erectile dysfunction in localized prostate carcinoma after robot assisted radical prostatectomy: Impact on management

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