Prostatic carcinoma: staging with MR imaging at 1.5 T.

Bezzi, Mario; Kressel, H Y; Allen, Kenneth S.; Schiebler, Mark L.; Altman, Howard; Wein, Alan J.; Pollack, Howard

doi:10.1148/radiology.169.2.3174982

Cited by 168 publications

(55 citation statements)

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“…It was confirmed that tu mors located ventrally and centrally in histopathologic specimens were Tumor volume is a predictor of pathologic stage (22). Except for one study performed with an externalarray coil (23), studies performed with endorectal coil (13) and body coil MR imaging (24)(25)(26)(27) reported a poor cor relation between MR tumor volume and the volume as calculated from the pathologic specimen. Mirowitz et al (6) who studied postcontrast Tlweighted images also reported poor correlation between the estimated and calculated volume.…”

Section: Discussionmentioning

confidence: 87%

Dynamic TurboFLASH subtraction technique for contrast-enhanced MR imaging of the prostate: correlation with histopathologic results.

Jager

Ruijter²,

Kaa³

et al. 1997

Radiology

219

114

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Section: Discussionmentioning

confidence: 87%

Dynamic TurboFLASH subtraction technique for contrast-enhanced MR imaging of the prostate: correlation with histopathologic results.

Jager

Ruijter²,

Kaa³

et al. 1997

Radiology

219

114

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“…IN PROSTATE IMAGING, anatomical details are excellently depicted by MRI using T2-weighted rapid acquisition with relaxation enhancement (RARE) (also known as T2W-TSE or T2W-FSE), which has been the gold standard (1,2).…”

mentioning

confidence: 99%

Three‐dimensional balanced steady state free precession imaging of the prostate: Flip angle dependency of the signal based on a two component T2‐decay model

Storås

Gjesdal²,

Gadmar

et al. 2010

Magnetic Resonance Imaging

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Purpose: To investigate the contrast of three-dimensional balanced steady state free precession (3D bSSFP) in the two component T2 model and to apply the results to optimize 3D bSSFP for prostate imaging at 1.5 Tesla. Materials and Methods:In each of seven healthy volunteers, six 3D bSSFP acquisitions were performed with flip angles (a) equally spaced between 10 and 110 . Predictions of signal and contrast were obtained from synthetic bSSFP images calculated from relaxation parameters obtained from a multi-spin-echo acquisition. One biexponential and two monoexponential models were applied. Measured and predicted signals were compared by simple linear regression. Results:The measured contrast to signal ratio increased continuously with a. Mean R 2 for the biexponential model was almost constant for a in the range 50-110 . The biexponential model was a better predictor of the measured signal than the monoexponential model. A monoexponential model restricted to the echoes TE ¼ 50-125 ms performed similar to the biexponential model. The predicted contrast peaked at a between 50 and 90 .Conclusion: Prostate imaging with bSSFP benefited from high flip angles. The biexponential model provided good signal prediction while predictions from the monoexponential models are dependent on the range of TE used for T2 determination. IN PROSTATE IMAGING, anatomical details are excellently depicted by MRI using T2-weighted rapid acquisition with relaxation enhancement (RARE) (also known as T2W-TSE or T2W-FSE), which has been the gold standard (1,2).Diagnostic performance has improved as new technological developments such as endorectal coil imaging and increasing field strengths has allowed for imaging at higher resolutions (2-4). The T2W-RARE applies a 2D sampling regime. Hence, imaging is constrained to relatively thick (>3 mm) slices. The diagnostic performance is expected to improve if throughplane image resolution is increased. To achieve thinner slices, a 3D sampling regimen is required. Ikonen et al (5) demonstrated thin-slice (1.5 mm) prostate imaging by applying the 3D dual-echo steady state (DESS) (6) technique. Further improvements in resolution may be gained by applying the simpler and more time-efficient balanced steady state free precession (bSSFP) sequence also known as balanced FFE, TrueFISP,. This technique is ideal for 3D scanning because it may be implemented with very short repetition time (TR) without loss of signal.The contrast of bSSFP has been thoroughly described (7-9). It is dependent on the tissue T2/T1-ratio, flip angle, and resonance offset. It has been shown that T2 decay in prostate tissue is of biexponential nature (10,11). The bSSFP signal may be predicted based on the results of the two component model. This presumably provides a more accurate tool for sequence optimization than the use of the monoexponential model.The aim of this work was to investigate the contrast of 3D bSSFP in the light of a two component T2 model and to apply the results to optimize high resolution 3D bSSFP for prostate im...

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“…[15][16][17][18] As a result, an endorectal coil was developed to better visualize the zonal architecture of the prostate and tumour in the periprostatic tissue and SVs. 19 Engelbrecht and colleagues found endorectal coil superiority in their meta-analysis, however, a similar systematic review revealed no difference between body and endorectal coil images.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic accuracy of surface coil magnetic resonance imaging at 1.5 T for local staging of elevated risk prostate cancer

Kim

Breau

Papadatos

et al. 2013

CUAJ

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Introduction: Preoperative prostate cancer stage predicts prognosis and affects treatment decisions. The purpose of this study was to estimate the sensitivity and specificity of surface coil magnetic resonance imaging (MRI) for prostate cancer stage using surgical pathologic data as the reference standard. Methods: High-risk patients (≥cT3 or PSA ≥20 ng/mL or Gleason ≥8) and selected intermediate-risk patients (clinically bulky disease on exam or biopsy, cT2b/c, or Gleason 7 with ≥3 of 5 biopsy cores positive in a lobe) routinely received a pelvic MRI at our institution. The images of identified patients were reviewed by one radiologist who was blinded to clinical information. The radiologist reported presence or absence of tumour within each lobe of the prostate. Extraprostatic extension (EPE), seminal vesicle (SV) invasion and pelvic lymph node (PLN) metastasis were also reported. Radiological findings were compared with prostatectomy pathology reports. Results: During the study period, about 320 radical prostatectomies were performed. Of these, 32 had a preoperative surface coil pelvic MRI adequate for analysis. Pathologically, 53 of 64 (82.8%) prostate lobes contained tumour, 17 (26.6%) lobes had associated EPE, 12 (18.8%) had SV involvement and 7 (10.9%) sets of PLNs contained cancer. Magnetic resonance imaging sensitivity and specificity were, respectively, 94.3% and 81.8% for tumour location, 82.4% and 87.2% for EPE, 83.3% and 92.3% for SV invasion and 71.4% and 94.7% for PLN involvement. Interpretation: Surface coil MRI accurately stages many prostate cancer patients with elevated risk of extraprostatic disease. This mode of imaging may be reasonable at centres that do not have endorectal coil MRI. RésuméIntroduction : Le stade du cancer de la prostate avant l'opération permet d'établir le pronostic et influe sur les décisions en ce qui concerne le traitement. Notre étude avait pour objectif d'évaluer la sensibilité et la spécificité de l'imagerie par résonance magnétique avec bobine de surface dans l'établissement du stade du cancer de la prostate en utilisant les données pathologiques liées à la chirurgie comme données de référence. Méthodologie : Les patients à risque élevé (tumeur ≥cT3 ou taux d'APS ≥20 ng/mL ou score de Gleason ≥ 8) et certains patients à risque intermédiaire (maladie volumineuse sur le plan clinique lors de l'examen ou à la biopsie, tumeur cT2b/c, ou score de Gleason de 7 avec au moins 3 carottes biopsiques sur 5 prélevées dans le même lobe qui soient positives) subissent un examen par IRM de façon systématique à notre établissement. Les images des patients inclus dans l'étude ont été examinées par un radiologiste à qui les données cliniques n'avaient pas été divulguées (examen à l'insu). Le radiologiste signalait la présence ou l'absence de tumeur dans chaque lobe prostatique. On a aussi signalé des cas d'extension extraprostatique, d'envahissement des vésicules séminales et de métastases touchant les ganglions lymphatiques pelviens. Les observations radiologiques ont été ...

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Prostatic carcinoma: staging with MR imaging at 1.5 T.

Cited by 168 publications

References 0 publications

Dynamic TurboFLASH subtraction technique for contrast-enhanced MR imaging of the prostate: correlation with histopathologic results.

Dynamic TurboFLASH subtraction technique for contrast-enhanced MR imaging of the prostate: correlation with histopathologic results.

Three‐dimensional balanced steady state free precession imaging of the prostate: Flip angle dependency of the signal based on a two component T2‐decay model

Diagnostic accuracy of surface coil magnetic resonance imaging at 1.5 T for local staging of elevated risk prostate cancer

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