“…The histometric module has been applied to breast epithelial preneoplastic lesions, ductal DCIS and infiltrating ductal breast cancer, and PIN lesions, as well as to solar keratotic skin lesions in the progression to basal cell cancer [25]. The diagnostic decision support modules have inference networks for prostatic [26,27], breast FNA cytologic specimen [28], and melanoma [29]. For the great variety of PIN lesions an inference network with expanded logical capabilities has been completed.…”