Prostatic lesions: A retrospective study of Turp Specimen

Abstract

Introduction: The term "prostate" is originally derived from the Greek word "prohistani", meaning "to stand in front of" [1]. It is one of the most commonly affected organs in elderly males,so early detection and management is required. Methods: The study includes 215 cases of TURP specimen for 2 years period from January 2017 to December 2018 received in department of pathology, D. Y. Patil Institute of Medical sciences and Hospital, Kolhapur. Hematoxylin and Eosin sections were examined. The clinical complaints and microscopic details were analysed and compared with similar studies. Malignancy was reported according to Gleasons score. Results: Of the total 215 TURP specimen, 179 (83.25%) were of nodular hyperplasia, 19 (8.8%) were of nodular hyperplasia with prostatitis, 3 (1.4%) were of prostatic intraepithelial neoplasia and 9 (4.18%) cases were malignant. Few cases were of granulomatous prostatitis in (2) and atypical adenomatous hyperplasia (1). All the 11 cases of prostate cancer were incidental carcinoma, 1 of which was poorly differentiated, 1 case was of well differentiated adenocarcinoma and 9 cases were of moderately differentiated adenocarcinoma. Conclusion: The present study showed that out of 215 cases of TURP, the most frequently encountered prostatic lesion were benign, out of which majority were BPH 83.25% commonly seen in the age group of 61-70 years. The malignant lesions were common more than 65 years of age. TURP is helpful in early identification of premalignant lesions and incidental prostate cancer.

A Retroprospective Clinicopathological Study of Prostatic Lesions in Surgical Specimens

“…Our results were in accordance with a study done by Sajjanar et al revealed that TURP chips comprised 83.7% of all 2,842 prostate specimens. 10 The majority of cases were benign lesions, of which nodular hyperplasia alone constituted 82% of cases, followed by 18% of prostatic adenocarcinoma. Our data are in agreement with the study by Muthuvel et al who showed that 92.98% of cases were of0 BPH followed by 7.02% of PAC cases.…”

“…Our results were in accordance with a study done by Sajjanar et al revealed that TURP chips comprised 83.7% of all 2,842 prostate specimens. 10…”