Prostatitis: imaging appearances and diagnostic considerations

Shakur, Amreen; Hames, Kiyomi Yamada; O’Shea, Aileen; Harisinghani, Mukesh G.

doi:10.1016/j.crad.2021.01.007

Cited by 12 publications

(4 citation statements)

References 39 publications

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“…Dynamic enhanced magnetic resonance imaging (DCE-MRI), most PCas show early enhancement in DCE, and a fast-rising and then declining outflow type curve, the DCE-MRI performance of prostate tuberculosis has not been reported systematically. [10] In this case, DCE-MRI appeared to have a significant enhancement in the prostate, which needs further study. Some MRS features have been reported to differentiate PTB from cancer.…”

Section: Discussionmentioning

confidence: 90%

Prostate tuberculosis mimicking prostate cancer: Case report and literature review

Li,

Dan,

Yang

et al. 2023

Medicine

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Rationale: Prostate tuberculosis (PTB) has no specific symptoms, or insidious presentation in male reproductive system tuberculosis, and is difficult to detect in the early stage. When PTB develops to the late stage, it leads to disease progression and irreversible organ and tissue damage. At present, the imaging manifestations of prostate tuberculosis vary and are not well known to imaging physicians and urologists. Diagnoses and Interventions: This case was a PTB patient, whose main manifestation was elevated serum prostate-specific antigen and the diagnosis was confirmed by ultrasound-guided prostate biopsy. We analyzed the imaging performance of various imaging techniques, and summarized and explored the imaging characteristics reported in the previous literature, with the aim of improving the early detection rate and providing evidence-based practice for early regular antituberculosis treatment in PTB. Outcomes: The multiparametric transrectal ultrasound performance of PTB is characteristic, and can be used for the differential diagnosis of prostate cancer causing elevated prostate-specific antigen levels in aged men.

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Section: Discussionmentioning

confidence: 90%

Prostate tuberculosis mimicking prostate cancer: Case report and literature review

Li,

Dan,

Yang

et al. 2023

Medicine

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“…To the best of our knowledge, prostatitis is a complex pathological process involving inflammation (27). In the present study, the prostatitis rat model was successfully constructed, and different concentration treatment of P1TCM was employed on rats.…”

Section: Discussionmentioning

confidence: 99%

Prostatitis No.1 traditional chinese medicine significantly exhibited anti-inflammation role on prostatitis through miR-205-5p/YES1

Jia Liu,

Yongchao Fan,

Ruiyu Song

et al. 2023

Cell Mol Biol (Noisy-le-grand)

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“…In addition, histopathology derived from transperineal mapping biopsy, instead of MRI-guided TB, was used as the reference. As shown in the Supplementary Table 1 , chronic prostatitis, which has been well described to have significantly diffuse morphology on MRI [ 25 , 26 ], was detected in 55% false-positive PI-RADS 5 lesions. This might explain why false-positive lesions in the present study are associated with larger lesion diameter.…”

Section: Discussionmentioning

confidence: 99%

Prediction of false-positive PI-RADS 5 lesions on prostate multiparametric MRI: development and internal validation of a clinical-radiological characteristics based nomogram

Cheng,

Fan,

et al. 2024

BMC Urol

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Background To develop a risk model including clinical and radiological characteristics to predict false-positive The Prostate Imaging Reporting and Data System (PI-RADS) 5 lesions. Methods Data of 612 biopsy-naïve patients who had undergone multiparametric magnetic resonance imaging (mpMRI) before prostate biopsy were collected. Clinical variables and radiological variables on mpMRI were adopted. Lesions were divided into the training and validation cohort randomly. Stepwise multivariate logistic regression analysis with backward elimination was performed to screen out variables with significant difference. A diagnostic nomogram was developed in the training cohort and further validated in the validation cohort. Calibration curve and receiver operating characteristic (ROC) analysis were also performed. Results 296 PI-RADS 5 lesions in 294 patients were randomly divided into the training and validation cohort (208 : 88). 132 and 56 lesions were confirmed to be clinically significant prostate cancer in the training and validation cohort respectively. The diagnostic nomogram was developed based on prostate specific antigen density, the maximum diameter of lesion, zonality of lesion, apparent diffusion coefficient minimum value and apparent diffusion coefficient minimum value ratio. The C-index of the model was 0.821 in the training cohort and 0.871 in the validation cohort. The calibration curve showed good agreement between the estimation and observation in the two cohorts. When the optimal cutoff values of ROC were 0.288 in the validation cohort, the sensitivity, specificity, PPV, and NPV were 90.6%, 67.9%, 61.7%, and 92.7% in the validation cohort, potentially avoiding 9.7% unnecessary prostate biopsies. Conclusions We developed and validated a diagnostic nomogram by including 5 factors. False positive PI-RADS 5 lesions could be distinguished from clinically significant ones, thus avoiding unnecessary prostate biopsy.

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Prostatitis: imaging appearances and diagnostic considerations

Cited by 12 publications

References 39 publications

Prostate tuberculosis mimicking prostate cancer: Case report and literature review

Prostate tuberculosis mimicking prostate cancer: Case report and literature review

Prostatitis No.1 traditional chinese medicine significantly exhibited anti-inflammation role on prostatitis through miR-205-5p/YES1

Prediction of false-positive PI-RADS 5 lesions on prostate multiparametric MRI: development and internal validation of a clinical-radiological characteristics based nomogram

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