Prosthetic and Extremity Survivorship After Limb Salvage for Sarcoma How Long Do the Reconstructions Last?

Horowitz, Stephen M.; Glasser, Dale B.; Lane, Joseph M.; Healey, John H.

doi:10.1097/00003086-199308000-00037

Cited by 88 publications

(103 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We observed that aseptic loosening is the most common late complication after distal femoral cemented endoprosthetic replacement, confirming other reports [4,9,16,18]. The reasons for aseptic loosening are removal of greater than 60% of the bone, patients younger than 20 years and increased offset of the tip of the prosthesis from the anatomical axis [3,4,18].…”

Section: Discussionsupporting

confidence: 89%

Distal femoral tumours treated by resection and custom mega-prosthetic replacement

Natarajan

Sivaseelam

Ayyappan

et al. 2005

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

We have analysed the results of 246 cases of distal femoral tumours treated by resection and prosthetic replacement between 1988 and 2002. Patient ages ranged from 6-67 years averaging 24 years; 133 were males. The most common tumour was osteosarcoma (67% of patients). The follow-up ranged from 2 to 14 years. Stage II tumours were seen in 72% of patients. The technique of sleeve resection of the quadriceps musculature was followed to achieve local clearance of the tumour. The prosthesis used was a rotating hinge custom mega-prosthesis manufactured locally. The functional result achieved was excellent or good in 87%; 86% of the patients had no evidence of disease, and 13% had died. The 10-year patient survival was 76.9%. Periprosthetic fracture and infection were the most common complications.Résumé Nous avons analysé les résultats de 246 cas de tumeurs fémorales distales traitées par résection et remplacement prothétique entre 1988 et 2002. L'âges des malades s'étendait de 6 à 67 ans avec une moyenne de 24 ans. Cent trente trois étaient des hommes. La tumeur la plus fréquente était l'ostéosarcome (67% des malades). Le suivi était de 2 à 14 années. Des tumeurs de stade II étaient présentes chez 72% des malades. La technique de résection a été conduite pour faire une ablation complète de la tumeur. La prothèse qui a été utilisée était une méga prothèse à charnière rotatoire fabriqué localement. Le résultat fonctionnel obtenu était excellent ou bon dans 87%. Quatre-vingt-six pourcent des malades n'avait pas d'évidence de maladie et 13% étaient morts. La survie à dix ans était de 76,9%. Les fractures périprothétiques et l'infection étaient les complications les plus fréquentes.

show abstract

Section: Discussionsupporting

confidence: 89%

Distal femoral tumours treated by resection and custom mega-prosthetic replacement

Natarajan

Sivaseelam

Ayyappan

et al. 2005

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

show abstract

“…Although we observed no differences between the Compress 1 and Stanmore cohorts, literature on other CIS implants without hydroxyapatite collars indicates the aseptic loosening rate generally increases with time [10,13,18,20,23,27]. Overall EPR survivability for distal femoral reconstruction varies greatly in the literature (Table 3).…”

Section: Discussionmentioning

confidence: 66%

“…Overall EPR survivability for distal femoral reconstruction varies greatly in the literature (Table 3). Published results show a survivorship of 75-90% at 5 years [10,13,15,16,20]. The 5-year survival of 83.5% in CPS implants is encouraging in light of these numbers.…”

Section: Discussionmentioning

confidence: 94%

Aseptic Failure: How Does the Compress® Implant Compare to Cemented Stems?

Pedtke

Wustrack

Fang

et al. 2012

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

Background Failure of endoprosthetic reconstruction with conventional stems due to aseptic loosening remains a challenge for maintenance of limb integrity and function. The Compress 1 implant (Biomet Inc, Warsaw, IN, USA) attempts to avoid aseptic failure by means of a unique technologic innovation. Though the existing literature suggests survivorship of Compress 1 and stemmed implants is similar in the short term, studies are limited by population size and followup duration.Questions/purposes We therefore compared (1) the rate of aseptic failure between Compress 1 and cemented intramedullary stems and (2) evaluated the overall intermediate-term implant survivorship. Methods We reviewed 26 patients with Compress 1 implants and 26 matched patients with cemented intramedullary stems. The patients were operated on over a 3-year period. Analysis focused on factors related to implant survival, including age, sex, diagnosis, infection, aseptic loosening, local recurrence, and fracture. Minimum followup was 0.32 years (average, 6.2 years; range, 0.32-9.2 years).

show abstract

“…Overall, 44 % of patients had at least one complication. In an attempt to determine prosthesis and extremity survivorship, Horowitz et al [25] reviewed their experience with 93 prosthetic reconstructions over 8 years: 16 proximal femur, 61 distal femur, and 16 proximal tibia. Minimum follow-up was 24 months (mean, 80 months).…”

Section: Discussionmentioning

confidence: 99%

Limb Salvage Surgery in Bone Tumors: A Retrospective Study of 50 Cases in a Single Center

Chauhan

Joshi

Chopra³

et al. 2013

Indian J Surg Oncol

View full text Add to dashboard Cite

Modular segmental replacement system (MSRS) is one of the options for Limb conservation surgery in bone tumors. The study analyses a single center experience of use of MSRS for limb conservation in cases of primary bone tumors. Retrospective analysis was done for a series of cases of limb salvage procedures done over a five year period. All Patients with bone tumors who underwent limb salvage procedures utilising MSRS prosthesis were included in the study. The patients' record were perused for pre operative staging; neoadjuvant therapy used, if any; surgical procedure done; follow-up for prosthesis related complications and overall survival achieved. Total of 50 cases studied,included 28 males and 22 females . Median age at diagnosis of 28 (10-73) years. Tumor localized in lower limb in 38 patients, and upper limb in 12 patients. Tumors were malignant in 28 patients (56 %) and benign in 22 (44 %). The most common diagnosis was osteosarcoma (21 patients (42 %)) . The median resection length was 15 cm (range 6-25). High grade tumors (grade 2a and 2b) was found in 27 of 29 cases(93.1 %) . 14 patients had prosthesis related complications. The mean follow-up was 5 years (range: 3-7). 42 patients of 50 were alive with the endoprosthesis at the last follow-up. Survival rate of prosthesis is 84 %. The modular segmental-replacement system prosthesis favoured by us in limb sparing surgery for bone tumors results in satisfactory results in terms of tumor control and limb function.

show abstract

Prosthetic and Extremity Survivorship After Limb Salvage for Sarcoma How Long Do the Reconstructions Last?

Cited by 88 publications

References 0 publications

Distal femoral tumours treated by resection and custom mega-prosthetic replacement

Distal femoral tumours treated by resection and custom mega-prosthetic replacement

Aseptic Failure: How Does the Compress® Implant Compare to Cemented Stems?

Limb Salvage Surgery in Bone Tumors: A Retrospective Study of 50 Cases in a Single Center

Contact Info

Product

Resources

About