Prosthetic Heart Valves

Pîbarot, Philippe; Dumesnil, Jean G.

doi:10.1161/circulationaha.108.778886

Cited by 645 publications

(239 citation statements)

References 83 publications

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“…Fixation causes crosslinking of collagen, which masks the antigens leading to reduced antigen presentation and chemical stabilization. It also leads to membrane damage leading to calcium influx [6]. This calcium combines with membrane phospholipids, and in the presence of mechanical stress leads to calcium phosphate crystal nucleation, crystal growth, and valve failure due to tears and stenosis [7].…”

Section: Fixation In Glutaraldehydementioning

confidence: 99%

Bioprosthetic Heart Valves: Impact of Implantation on Biomaterials

2013

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Prosthetic heart valves are commonly used in the treatment of valvular heart disease. Mechanical valves are more durable than the bioprosthetic valves; however, the need for long-term anticoagulant therapy renders them unsuitable for some patient groups. In this paper we discuss the different types and models of bioprosthesis, and in particular, pericardial bioprosthesis. We also discuss the preimplantation preparation processes, as well as their postimplantation changes and modes of failure.

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Section: Fixation In Glutaraldehydementioning

confidence: 99%

Bioprosthetic Heart Valves: Impact of Implantation on Biomaterials

2013

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“…Other valves are being clinically evaluated, which will incorporate other means to facilitate proper positioning and reduce paravalvular leaks. The new generation of valves with greater expansion force may dismiss the use of the balloon and favor valve fi xation 41 . Although these valves are contributing to the treatment of aortic stenosis, discretion of information on effectiveness, durability, and results may lead to unexpected problems 30 .…”

Section: Discussionmentioning

confidence: 99%

Manejo anestésico e complicações no implante percutâneo de válvula aórtica

Grando¹,

Sarmento‐Leite²,

Prates³

et al. 2013

Rev. Bras. Anestesiol.

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Background and objective: Aortic stenosis is a highly prevalent and life-threatening disease. In elderly patients with comorbidities, percutaneous valve implantation is an option. The aim of the study was to describe the anesthetic management and complications of general anesthesia. Method: Case series with 30-day and 24-month follow-ups after implantation of the CoreValve device performed at the Institute of Cardiology/University Foundation of Cardiology between December 2008 and January 2012. The patients underwent general anesthesia monitored with mean arterial pressure (PAM), electrocardiogram (ECG), pulse oximetry, capnography, transesophageal echocardiography, thermometry, and transvenous pacemaker. Results: Twenty-eight patients, mean age 82.46 years, 20.98% mean EuroSCORE, functional class III/IV, successfully underwent valve implantation. Nine patients required permanent pacemaker implantation. During follow-up, two patients died: one during surgery due to LV perforation and the other on the third day of unknown causes. At 24 months, one patient diagnosed with multiple myeloma died. This anesthetic technique proved to be safe. Conclusion: The initial experience with percutaneous aortic valve implantation under general anesthesia has proven to be safe and effective, with no signifi cant anesthetic complications during this procedure.

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“…Through the use of a tubular design, the valve preserves the aortic sinuses, restores the native stress distribution to the entire aortic root, and provides excellent hemodynamics by restoring physiologic and non-turbulent transvalvular flow while maintaining coronary perfusion. 21,64,85 Finally, the Freestyle is a stentless bioprosthesis that aims to replicate human physiology while offering excellent durability. 7 As a full root replacement, the Freestyle offers a great deal of surgical versatility.…”

Section: Bioprosthetic Heart Valvesmentioning

confidence: 99%

Emerging Trends in Heart Valve Engineering: Part II. Novel and Standard Technologies for Aortic Valve Replacement

et al. 2014

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Abstract-The engineering of technologies for heart valve replacement (i.e., heart valve engineering) is an exciting and evolving field. Since the first valve replacement, technology has progressed by leaps and bounds. Innovations emerge frequently and supply patients and physicians with new, increasingly efficacious and less invasive treatment options. As much as any other field in medicine the treatment of heart valve disease has experienced a renaissance in the last 10 years. Here we review the currently available technologies and future options in the surgical and transcatheter treatment of aortic valve disease. Different valves from major manufacturers are described in details with their applications.

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Prosthetic Heart Valves

Cited by 645 publications

References 83 publications

Bioprosthetic Heart Valves: Impact of Implantation on Biomaterials

Bioprosthetic Heart Valves: Impact of Implantation on Biomaterials

Manejo anestésico e complicações no implante percutâneo de válvula aórtica

Emerging Trends in Heart Valve Engineering: Part II. Novel and Standard Technologies for Aortic Valve Replacement

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