Prosthetic management of atrophic rhinitis

Kumar, Namburi Suneel; Tripuraneni, Satish Chandra

doi:10.1007/s12070-008-0120-z

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…A los dos meses de seguimiento, presentó disminución de la obstrucción nasal y cefalea, observándose cavidades nasales limpias y ausencia de costras y mal olor. A los 10 meses se describió que se encontraba libre de enfermedad 28 .…”

Section: Obturadores Y Stents Nasalesunclassified

Historia del manejo de rinitis atrófica

et al. 2020

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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Section: Obturadores Y Stents Nasalesunclassified

Historia del manejo de rinitis atrófica

et al. 2020

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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Is submucosal fat injection effective in atrophic rhinitis? An experimental animal study

Balur

Koçak

Altınay

et al. 2017

Eur Arch Otorhinolaryngol

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Atrophic rhinitis (AR) is a disease characterized by the extensive dilatation of the nasal cavity and atrophy of the mucosa, submucosa and bone tissue. Its etiological factors are unknown. There is not a satisfying treatment yet and the treatment of the functional impairment in the atrophic cells is still subject to investigation. The objective of this study is to determine at the histopathological level the possible effects of the submucosal fat injection in an experimental model of AR. 12 albino Wistar-Hannover male rats were included in the study. AR was induced with the Pasteurella multocida toxin, which was diluted with saline. As one of the rats died during the study, it was excluded from the evaluation. The right nasal cavities of all rats (11 nasal cavities) were defined as the control group (Group 1). Fat tissue obtained from the abdominal area was injected in the seven left nasal cavities (Group 2). All injections, which were done to the abdominal regions were also done in the left nasal cavities of the remaining four rats, which constituted the sham group (Group 3). After 14 days, all rats were decapitated and the squamous metaplasia and keratinization in the superficial epithelium, degeneration, vacuolar changes in the basal layer, congestion, inflammatory infiltration, vascular proliferation and glandular atrophy in the submucosa are histopathologically classified. The results were analyzed with statistical methods. Although glandular atrophy was significantly regressed in the fat injection group (Group 2) compared to other groups (p < 0.05), the remaining parameters did not show any significant difference among these three groups. The histopathological effect of the fat injection was modest. We concluded that fat injection treatment has no or at the most a very limited effect in the treatment of atrophic rhinitis.

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