“…[192][193][194] Milder acute attacks may settle spontaneously. More severe cases will become protracted and may be complicated by a number of serious problems such as flaccid quadriparesis, 31,182,195,196 seizures, 155,181,[195][196][197] encephalopathy, severe hyponatremia, 139,155,197 and the posterior reversible encephalopathy syndrome. 195,[198][199][200] In our experience, seizures, which are uncommon, are often secondary to factors such as hyponatremia 155,172 and the use of meperidine in high doses.…”