Protection of Chicks Against E. coli Infection by Dietary Supplementation with Vitamin E

Heinzerling, Rollin H.; Nockels, C. F.; Quarles, C. L.; Tengerdy, Robert P.

doi:10.3181/00379727-146-38087

Cited by 77 publications

(26 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the immune response of hens and their offspring fed rations with no vitamin E supplementation and stressed with 10% fish oil (vitamin E calculated at 8 to 10 mg/kg) was not reduced below that of birds receiving rations containing 10% soybean oil and vitamin E addition (calculated at 76 mg/kg) despite rapid decline in egg production and hatch of fertile eggs on the stressed ration. Heinzerling et al (1974) cited previous work of their laboratory that selenium alone at levels above .1 ppm or in combination with vitamin E also enhanced immune response of mice but that synthetic antioxidants did not do so. Tengerdy and Nockels (1973) referred to research by their group showing that after exposure of chickens to oxygen insufficiency, the resulting hypoxia stimulated immune response, despite the derpessing effect on hatchability, and that hypoxia and vitamin E 7.2 e 9.8 9.8…”

Section: Effects Of Infection On Apparent Vitamin Requirementsmentioning

confidence: 90%

“…The findings of Heinzerling et al (1974) in Table 7 show that vitamin E supplementation of a practical ration, inferred to contain 43 mg vitamin E/kg, sharply reduced mortality and significantly improved weight gains and blood titers in chicks in which a moderately severe infection of E. coli was induced. The effectiveness of adding 150 mg of vitamin E/kg to the ration agrees with their earlier work, cited by them, of similar additons response of chicks and of mice against sheep red blood cells (RBC) and of mice against tetanus toxoid.…”

Section: Effects Of Infection On Apparent Vitamin Requirementsmentioning

confidence: 94%

“…Panda et al (1964) reported that the severe depletion at this stage was accompanied by hypertrophy of the liver. Hill (1962) Hill (1962) Hill (1962) Hill (1962 Hill and Garren (1958) Hill (1962) Hill (1962) Hill (1962) Hill (1962) Hill (1962 Panda and Combs(1963) Panda and Combs (1963) Panda and Combs (1963) Tagwerker (1962) Squibb et al (1955) Tagwerker (1962) Squibb et al (1955) Squibb et al (1955) Tagwerker (1962) Squibb et al (1955) Squibb et al (1955) Squibb et al (1955 Boyd and E.dwards (1962) Heinzerling et al (1974) Tagwerker (1962 Abbotts al. (1960) Boyd and Edwards (1962) Pantothenic acid.…”

Section: Survey Of Evidencementioning

confidence: 96%

See 2 more Smart Citations

Disease, Nutrition—Interaction

Wilgus

1980

Poultry Science

View full text Add to dashboard Cite

Practical implications of interactions between disease and vitamins in poultry were sought in the readily available literature. The evidence, almost exclusively in chickens, is in accord with that reported in other animals and man, namely 1) dietary vitamin deficiencies can impair body defense mechanisms against disease and 2) occurrence of disease can increase vitamin requirements.Information on viral infections is inadequate and conflicting. Slight indications exist for positive interactions with ascorbic acid and for antagonistic ones with vitamin A.Studies on bacterial diseases involved 7 organisms, 11 vitamins, and 29 observations of which 25 (86%) indicated positive interactions. Those on parasitic infestations involved 9 organisms, 9 vitamins, and 55 observations of which 45 (82%) indicated interactions. The major evidence for interaction between individual vitamins and disease categories was for vitamin A and ascorbic acid in bacterial infections and for vitamins A and K in parasitic infestations.The numbers of confirming studies on individual diseases and vitamins deemed to be reasonably adequate to demonstrate specific interactions were limited to vitamin A in coccidiosis, in ascariasis, and probably in infectious coryza and of vitamin K in coccidiosis.Despite the paucity of specific and quantitative evidence, it appears likely that vitamin levels in chick rations containing generous margins of safety, as referred, should be adequate to meet the increased requirements caused by most diseases. However, when liver reserves of vitamin A are depleted, notably by severe coccidiosis, the effects may be ameliorated and recovery may be aided by additional vitamin A and possibly other fat-soluble vitamins. Decision for such augmentation, selection of formulation, and mode and duration of administration require collaboration of the pathologist and nutritionist familiar with the particular circumstances.It has not been proven that vitamins exert a pharmacodynamic effect or that they will replace the use of appropriate prophylactic or therapeutic drugs. Multidisciplinary research on specific nutrient requirements as affected by specific disease entities is sorely needed.

show abstract

Section: Effects Of Infection On Apparent Vitamin Requirementsmentioning

confidence: 90%

Section: Effects Of Infection On Apparent Vitamin Requirementsmentioning

confidence: 94%

Section: Survey Of Evidencementioning

confidence: 96%

See 1 more Smart Citation

Disease, Nutrition—Interaction

Wilgus

1980

Poultry Science

View full text Add to dashboard Cite

show abstract

“…to have no effect, or to depress proliferation of lymphocytes in vitro.2:3.25.26 Parenteral vitamin E supplementation every other day for 2 weeks following 20% TBSA steam burn to mice improved the delayed-type hypersensitivity (DTH) response to dinitrofluorobenzene (DNFB).27 Vitamin E supplementation also improves both primary and secondary antibody production. 7,9,[28][29][30][31] Of interest are the observations in this study that increasing amounts of vitamin E do not sustain the beneficial effects of the moderate supplemental dose. Heinzerling and associates supplemented the solid diets of chicks with vitamin E prior to parenteral challenge with E. coli, and did not observe a loss of beneficial effect as the dose was increased from 150 mg of vitamin E per kg of chow to 300 mgjkg.7 However, the same group found varying efficacy of supplemental vitamin E added to the solid diets of mice fed prior to challenge with D.…”

Section: E21mentioning

confidence: 93%

Survival in Septic Guinea Pigs Is Influenced by Vitamin E, but Not by Vitamin C in Enteral Diets

Peck

Alexander

1991

J Parenter Enteral Nutr

View full text Add to dashboard Cite

Oxygen-free radicals are produced during sepsis, and may contribute to cell injury and dysfunction. We studied the effect of different levels of vitamins E and C in the diet fed enterally to septic guinea pigs. Sixty-four female guinea pigs were provided with gastrostomies and allowed to recover. Intraperitoneal osmotic pumps were then implanted that provided effusion of Escherichia coli and Staphylococcus aureus for the next 7 days. Three days after pump implantations, the animals were started on one of nine diets. The diets were isocaloric and isonitrogenous, and differed only in the amounts of vitamins E and C. Three levels of each vitamin were used, based on the Recommended Daily Allowance (RDA). The feedings were continued for 2 weeks, during which time mortality was observed. The amount of vitamin C had no effect on outcome, with mortality rates of 68% (15/22) in the 1 x RDA group, 73% (16/22) in the 5 x RDA group, and 65% (13/20) in the 25 x RDA group. However, vitamin E altered outcome significantly, with mortality rates of 86% (18/21) in the 1 x RDA group, 45% (10/22) in the 3 x RDA group, and 76% (16/21) in the 9 x RDA group. Mortality in the 3 x RDA group was significantly lower than that in the 1 x RDA group and in the 9 x RDA group.(ABSTRACT TRUNCATED AT 250 WORDS)

show abstract

“…This implies that vitamin E possesses the inherent potential to protect the reproductive tissues against many chemical as well as infectious pathologies (Pham-Huy et al, 2008). Vitamin E supplementations increase the resistance of chicks against Escherichia coli (Heinzerling et al, 1994) and of lambs against Chlamydia infection (Stephens and Nockles, 1979). Pigs supplemented with vitamin E and selenium had increased phagocytic activity of the reticuloendothelial system (Heinzerling et al, 1994).…”

Section: Specimen Collection and Analysismentioning

confidence: 99%

Effects of Vitamin E Supplementation in Male Rats with Crude Oil-Induced Reproductive Toxicity

et al. 2017

View full text Add to dashboard Cite

Crude oil intoxication is a major threat among people and animals living around the crude oil producing regions of the world, hence the search for ameliorating agents. Forty-four male Wistar rats assigned to three groups were used to investigate the effects of vitamin E supplementation on crude oil-induced reprotoxicity (reproductive toxicity) in male rats. Group A represented the unexposed control, whereas groups B and C were exposed orally to 0.15 and 0.3 ml of crude oil respectively every other day, for 56 days. Both the low dose and high dose oral administration of crude oil caused a significant reduction in the serum testosterone level (STL) and cauda epididymal sperm reserve (CESR) of the exposed rats when compared to the control. Crude oil withdrawal and vitamin E supplementation significantly improved the cauda epididymal sperm reserve (CESR) in all the subgroups. The serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities of the control and low dose group were significantly lower than those of the high dose group. The high dose crude oil administration significantly decreased the mean serum total protein (STP) and sodium ions (Na + ) concentration. The mean serum total cholesterol (STC) value of the low dose group was significantly higher than those of the control and high dose group. However, crude oil withdrawal and vitamin E supplementation did not significantly alter the mean serum total protein (STP) and mean serum total cholesterol (STC) values in all the subgroups. Vitamin E supplementation following low dose crude oil withdrawal enhanced the mean serum Chloride ions (Cl -) concentration. The present findings revealed that Nigerian Qua Iboe Brent crude oil induced serious reprotoxic effects in male rats which vitamin E administration within 28 days did not completely reverse.

show abstract

Protection of Chicks Against E. coli Infection by Dietary Supplementation with Vitamin E

Cited by 77 publications

References 0 publications

Disease, Nutrition—Interaction

Disease, Nutrition—Interaction

Survival in Septic Guinea Pigs Is Influenced by Vitamin E, but Not by Vitamin C in Enteral Diets

Effects of Vitamin E Supplementation in Male Rats with Crude Oil-Induced Reproductive Toxicity

Contact Info

Product

Resources

About