Protective and Recovery Effects of Resveratrol Supplementation on Exercise Performance and Muscle Damage following Acute Plyometric Exercise

Abstract

Plyometric exercise (PE) is an effective training method to increase muscle mass and strength. However, excessive or inappropriate conditions might cause exercise-induced muscle damage (EIMD). Resveratrol (RES) is a natural polyphenol plant antitoxin, which improves exercise performance, and exhibits anti-oxidation, anti-inflammatory, and anti-cancer effects. Therefore, this study investigated the effect of RES supplementation on the recovery of muscle damage, inflammation, soreness, muscle power, and anaerobic performance following plyometric-exercise-induced muscle damage (PEIMD). The present study was a double-blind, placebo-controlled research trial. Thirty-six young, untrained males were enrolled into the placebo (n = 12), RES-500 (500 mg RES/day, n = 12), or RES-1000 (1000 mg RES/day, n = 12) group by a jumping height-counterbalanced grouping design. At baseline, to pre-PEIMD, supplements were pre-loaded 7 days before they conducted PEIMD, and the exercise performance, delayed-onset muscle soreness (DOMS) and muscle damage biomarkers were measured over the experimental period at baseline, pre-PEIMD, and post-PEIMD at 2, 24, 48, and 72 h. As a result, we found that, at 72 h post-EIMD, the force peak (FP) and rate of force development (RFD) of the counter movement jump (CMJ) in RES groups showed no significant difference compared to that at baseline but was significantly greater than the placebo group. In the Wingate anaerobic test (WAnT), supplementation in the RES group had a better recovery effect on the relative peak power (RPP), relative mean power (RMP) and fatigue index (FI) (p < 0.05), especially in the high-dose group. For the detection of muscle pain after PEIMD, the RES supplement group was significantly better than the placebo group (p < 0.05). In addition, for muscle damage indexes, such as creatine kinase (CK) and lactate dehydrogenase (LDH), after PEIMD, supplementation with RES could significantly reduce and accelerate recovery (p < 0.05). In addition, the blood biochemical indicators of blood count, liver function, and kidney function showed that RES will not cause adverse risks to the human body. Our results suggest that replenishing RES in advance could effectively reduce muscle pain, increase exercise performance, and decrease muscle damage indicators caused by PEIMD, and the recovery was faster. Therefore, plyometric exercises combined with suitable RES supplementation could be an effective candidate for controlling muscle damage, improving physical adaption, and recovering anaerobic capacity.

Resveratrol and Wine: An Overview of Thirty Years in the Digital News

“…Contrarily, other pre-clinical [ 54 , 55 , 56 , 57 , 58 ] or clinical studies [ 59 , 60 ] did not find any deleterious effect of resveratrol supplementation on exercise performance, independently of its effect as an ergogenic aid. Thus, in a dose-dependent manner, the administration of resveratrol in combination with several training programs (plyometric exercise, high-intensity cycling, resistance training, …) shows positive effects, such as a reduction in the decline in strength performance [ 59 ], a reduction in pain or damage indexes [ 59 ], a reduction in the inflammation induced by plyometric-exercise-induced muscle damage [ 59 ] or exercise-induced inflammation [ 60 ], or fatigue [ 56 , 58 ] markers, and it could accelerate recovery [ 59 ] or increase grip strength [ 55 , 56 , 58 ], contractile force [ 54 ], or aerobic performance [ 55 ].…”

Live and Heat-Killed Probiotic Lactobacillus paracasei PS23 Accelerated the Improvement and Recovery of Strength and Damage Biomarkers after Exercise-Induced Muscle Damage

“…We refer to the way in which EIMD was successfully induced in the past [ 32 , 34 ]. All subjects were asked to perform 100 maximal vertical jumps.…”

“…Afterwards, they were instructed to squat until their knees were bent 90 degrees, then immediately jump as high as possible with maximum force. Each participant performed 3 replicates; we obtained CMJ data at the designated points and calibrated the instrument for each individual’s weight [ 34 ]. The measured parameters were rate of force development (RFD), relative peak force, and jump height.…”

“…We started measuring after warming up. When the subject sprinted at 120 rpm, a weight set to 7.5% of their body weight (for example, a 60 kg person would add 4.5 kg of resistance) automatically landed on the bike’s friction belt, creating additional resistance [ 34 ]. We continued asking the subject to sprint at full strength for 30 s. The measured parameters were relative mean power (W/kg), relative peak power (W/kg), and fatigue index (%).…”

Effects of a natural nutritional supplement on immune cell infiltration and immune gene expression in exercise-induced injury

“…In addition, dietary supplements that relieve pain and discomfort after sports injuries and promote injury repair have fewer side effects than, for example, NSAIDs, and are more effective in improving physical fitness (17). Natural ingredients, such as curcumin, quercetin, and resveratrol, are a great treasure trove and have been found to be effective for sports injuries (18)(19)(20). Our previous studies have found that Rhodiola rosea as a natural supplement has a positive effect on exercise capacity and performance, reduces post-exercise pain and skeletal muscle injury, and enhances antioxidant capacity (21).…”