Protective capacity in stroke treatment of AZD6482-loaded platelet membrane-coated γ-Fe2O3

Lv, Luting; Liu, Tingting; Zhang, Tengteng; Sun, Jinghui; Sang, Junzhi; Wang, Hongwei; Qian, J.

doi:10.1016/j.jddst.2023.104783

Journal of Drug Delivery Science and Technology

2023

DOI: 10.1016/j.jddst.2023.104783

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Protective capacity in stroke treatment of AZD6482-loaded platelet membrane-coated γ-Fe2O3

Luting Lv

Tingting Liu

Tengteng Zhang

et al.

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2024

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A Review: Surface Engineering of Lipid‐Based Drug Delivery Systems

Patel,

Solanki,

Kher

et al. 2024

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This review explores the evolution of lipid‐based nanoparticles (LBNPs) for drug delivery (DD). Herein, LBNPs are classified into liposomes and cell membrane‐based nanoparticles (CMNPs), each with unique advantages and challenges. Conventional LBNPs possess drawbacks such as poor targeting, quick clearance, and limited biocompatibility. One of the possible alternatives to overcome these challenges is surface modification of nanoparticles (NPs) with materials such as polyethylene glycol (PEG), aptamers, antibody fragments, peptides, CD44, hyaluronic acid, folic acid, palmitic acid, and lactoferrin. Thus, the main focus of this review will be on the different surface modifications that enable LBNPs to have beneficial properties for DD, such as enhancing mass transport properties, immune evasion, improved stability, and targeting. Moreover, various CMNPs are explored used for DD derived from cells such as red blood cells (RBCs), platelets, leukocytes, cancer cells, and stem cells, highlighting their unique natural properties (e.g., biocompatibility and ability to evade the immune system). This discussion extends to the biomimicking of hybrid NPs accomplished through the surface coating of synthetic (mainly polymeric) NPs with different cell membranes. This review aims to provide a comprehensive resource for researchers on recent advances in the field of surface modification of LBNPs and CMNPs. Overall, this review provides valuable insights into the dynamic field of lipid‐based DD systems.

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A Review: Surface Engineering of Lipid‐Based Drug Delivery Systems

Patel,

Solanki,

Kher

et al. 2024

Small

View full text Add to dashboard Cite

show abstract

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Protective capacity in stroke treatment of AZD6482-loaded platelet membrane-coated γ-Fe2O3

Cited by 1 publication

References 26 publications

A Review: Surface Engineering of Lipid‐Based Drug Delivery Systems

A Review: Surface Engineering of Lipid‐Based Drug Delivery Systems

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