Protective Effect of Catheter Ablation of Atrial Fibrillation on the Renal Function in Patients With Hypertrophic Cardiomyopathy

Mimuro, Rei; Hayashi, Hiroshi; Iwasaki, Yu‐ki; Hachisuka, Masato; Fujimoto, Yuhi; Oka, Eiichiro; Murata, Hiroshige; Yamamoto, Teppei; Yodogawa, Kenji; Shimizu, Wataru

doi:10.1016/j.amjcard.2022.02.055

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…However, the success rates of CA in patients with HCM are lower than in patients without HCM (6,7), and continued procedures after initial treatment are often necessary to restore long-term sinus rhythm (8). One previous report with a propensity score (PS)-matched suggested that CA protected the renal function (9); however, data on long-term clinical outcomes of patients with HCM undergoing radiofrequency catheter ablation (RFCA) are not well-established. The present study aimed to investigate the electrophysiological characteristics of recurrent AF and the impact of RFCA on long-term outcomes of patients with HCM compared with patients undergoing pharmacological treatment alone.…”

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confidence: 99%

Catheter ablation in Asian patients with atrial fibrillation and hypertrophic cardiomyopathy: electrophysiological characteristics of recurrence and long-term clinical outcomes

Lin

Chung

et al. 2023

Front. Cardiovasc. Med.

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BackgroundCatheter ablation (CA) is a treatment strategy for atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). We investigated the electrophysiological characteristics of recurrence in a tertiary referral center and compared long-term clinical outcomes after CA therapy with patients who did not undergo CA.MethodsPatients with HCM and AF who underwent CA (group 1, n = 60) or pharmacological treatment (group 2, n = 298) between 2006 and 2021 were enrolled in this study. The baseline characteristics and electrophysiological characteristics of group 1 patients were examined to elucidate the reason for the recurrence of AF after CA therapy. The clinical results of the patients in Group 1 and Group 2 were compared using a propensity score (PS)-matched method.ResultsThe most common cause of recurrence was pulmonary vein reconnection (86.5%), followed by non-pulmonary vein triggers (40.5%), cavotricuspid isthmus flutter (29.7%), and atypical flutter (24.3%). Thyroid disease (HR, 14.713; P < 0.01), diabetes (HR, 3.074; P = 0.03), and non-paroxysmal AF (HR, 4.012; P = 0.01); these factors independently predicted recurrence. After the first recurrence, patients who underwent repeat CA showed a better arrhythmia-free state (74.1%) than those who underwent drug escalation therapy (29.4%, P < 0.01). After matching, PS-group 1 patients showed significantly better outcomes in all-cause mortality, heart failure hospitalization, and left atrial reverse remodeling than PS-group 2 patients.ConclusionsPatients who underwent CA showed better clinical outcomes than those who underwent drug therapy. The main predictors of recurrence were thyroid disease, diabetes, and non-paroxysmal AF.

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Section: Introductionmentioning

confidence: 99%

Catheter ablation in Asian patients with atrial fibrillation and hypertrophic cardiomyopathy: electrophysiological characteristics of recurrence and long-term clinical outcomes

Lin

Chung

et al. 2023

Front. Cardiovasc. Med.

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Research Advances of Catheter Ablation Improving Renal Function Impairment in Patients with Atrial Fibrillation

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2024

ACM

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Protective Effect of Catheter Ablation of Atrial Fibrillation on the Renal Function in Patients With Hypertrophic Cardiomyopathy

Cited by 2 publications

References 29 publications

Catheter ablation in Asian patients with atrial fibrillation and hypertrophic cardiomyopathy: electrophysiological characteristics of recurrence and long-term clinical outcomes

Catheter ablation in Asian patients with atrial fibrillation and hypertrophic cardiomyopathy: electrophysiological characteristics of recurrence and long-term clinical outcomes

Research Advances of Catheter Ablation Improving Renal Function Impairment in Patients with Atrial Fibrillation

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