2023
DOI: 10.21203/rs.3.rs-2812492/v1
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Protective Effect of Ginsenoside Rg5 on Hypoxia/Reoxygenation- Induced H9c2 Cardiomyocytes by Correcting Free Fatty Acids β- oxidation

Abstract: Clinically, the in-hospital mortality rate of cardiogenic shock (CS) is approximately 50%. In CS, metabolic pathways in the body undergo “embryonal transformation,” in which metabolic processes transform free fatty acids (FFAs) to glucose. Shenfu injection (SFI) treatment has exhibited a positive effect on cardiogenic shock, and ginsenoside Rg5 (G-Rg5) is the anticardiogenic shock component of SFI. In this study, we aimed to investigate the myocardial protective effect and mechanism of G-Rg5 in myocardial ener… Show more

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