Protective effect of magnesium and metformin on endometrium and ovary in experimental diabetes mellitus

Galeş, Cristina; Zamfir, C; Rădulescu, D; Stoica, Bogdan; Nechifor, M

doi:10.1684/mrh.2014.0363

Cited by 6 publications

(2 citation statements)

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“…These findings present that the main response of fiscal and monetary policies, as well as the response of international factor on the inflation rate, are long-run asymmetry. This finding is in line with the previous research for the case of Iran (Falahi & Hajamini, 2017). More specifically, the effect of increases and decreases in each variable (government expenditure, money supply, and exchange rate) of the same magnitude on inflation has a different magnitude.…”

Section: Journal Of International Studiessupporting

confidence: 92%

Price stabilization policy in an emerging economy: An asymmetric approach

Sriyana¹

2019

Journal of International Studies

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Price stabilization has been an important issue for Indonesian monetary authority for decades. Relatively high inflation rates in the recent years following a series of financial crises have characterized Indonesian economy. The aim of this paper is to investigate the determinants of inflation dynamics based on the annual data for the period of 1970-2017. The nonlinear autoregressive distributed lag (NARDL) model is applied to identify the dynamic effects of government expenditure, money supply, and exchange rate on the inflation rate. The research finds that the mentioned variables significantly affect the inflation rate. Moreover, the dynamic effects of these variables on the inflation rate are asymmetric in the long run. Positive changes in government expenditure and money supply have a long-run impact on the increase of inflation rate. The increase in inflation rate is also associated with currency depreciation. The international financial market dynamics affects the inflation rate in the country through asymmetric effects of exchange rate volatility. This paper also highlights that government expenditure and money supply are effective instruments for price stabilization, with their asymmetric effects taken into consideration. The evidence of the short-run symmetric impact from those variables implies that fiscal and monetary authorities should have a quick response to the price stabilization.

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Section: Journal Of International Studiessupporting

confidence: 92%

Price stabilization policy in an emerging economy: An asymmetric approach

Sriyana¹

2019

Journal of International Studies

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“…However, the mechanisms responsible for the pathogenesis of diabetesinduced infertility are not fully clear (17). Folliculogenesis and steroidogenesis deterioration, anovulation and stromal fi brosis may develop due to hyperglycemia (18,19). It is very important to elucidate the molecular mechanisms underlying such diabetic disorders.…”

Section: Discussionmentioning

confidence: 99%

Alterations in the immunoreactivity of laminin, type IV collagen and α3β1 integrin in diabetic rat ovarian follicles

Yıldırım¹,

Karabulut²,

Öztürk³

et al. 2020

BLL

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In order to determine the possible effects of diabetes, we aimed to investigate the expression of extracellular matrix proteins in the theca and granulosa layers in different follicular stages. METHODS: Thirty-two adult Wistar albino male rats were divided into 4 groups as control and sampled groups. Four, eight and twelve weeks after inducing diabetes with an intraperitoneal injection of streptozotocin (40 mg/kg), the expressions of laminin, type IV collagen and α3β1 integrin in ovarian tissues were evaluated by immunohistochemical method. RESULTS: In our study, in the fi rst month of diabetes, a signifi cant increase was observed in laminin, type IV collagen and α3β1 integrin expressions in all follicle types compared to the control group in both the theca and granulosa layers. Laminin and type IV collagen immunoreactivity tended to increase in D2 and D3 groups also. Integrin expression did not change in the newly formed follicles in the D2 and D3 groups, however, it tended to change and increase in the developing follicles. CONCLUSIONS: The changes in the expression of laminin, type IV collagen and α3β1 integrin, which are the extracellular matrix proteins in the follicle, along with diabetes, show that diabetes plays a role in the regulation of follicular development (Tab. 4, Fig. 36, Ref.

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