Protective effect of oxytocin on ovarian ischemia-reperfusion injury in rats

The protective effect of Gingko biloba in a rat model of ovarian ischemia/reperfusion injury: Improvement in histological and biochemical parameters

“…In several recent studies, MDA was used to evaluate tissue injury induced by I/R oxidative stress. [8][9][10] In our study, the elevated MDA levels in the torsion and torsion/de-torsion groups were consistent with the literature. Furthermore, the GB rats had significantly lower MDA levels.…”

Oxytocin in The Prevention of Injury Due to Testicular Torsion/Detorsion in Rats

“…[54][55][56][57][58] In addition, the anti-apoptotic effect of oxytocin in the heart and ovaries has been revealed. [51,59] However, to our knowledge, the effect of oxytocin on testicular tissues in I/R injured rat model has been reported in only one study. In an experimental study, Ghasemnezhad et al demonstrated that Johnsen scores were higher in the oxytocin-treated torsion group than in the testicular torsion group.…”

Uterotonik Bir Ajandan Fazlası: Oksitosin Postoperatif Adezyonları Önlüyor

“…However, they suggested that OT application prevented the rising of OS. The previous studies also reported the protective effect of OT on ischemia reperfusion-related injuries in ovaries, heart and skeletal muscle [7,9,28] . In our study we also detected the protective effect of OT on inflammation, neo-vascularization, fibrosis, and then adhesion formation.…”

“…Oxytocin was used intraperitoneally at the dose of 80 IU/kg, which was the same dose used in the previous study [28] . It has been shown that high doses of OT have some side effects in humans such as cardiac arrhythmia, fatal afibrinogenemia, nausea, vomiting, premature ventricular contractions, subarachnoid hemorrhage, and hypertensive episodes.…”