Protective effect of red orange extract supplementation against <scp>UV</scp>‐induced skin damages: photoaging and solar lentigines

Puglia, Carmelo; Offerta, Alessia; Saija, Antonella; Trombetta, Domenico; Cardile, Venera

doi:10.1111/jocd.12083

Cited by 50 publications

(39 citation statements)

References 17 publications

(56 reference statements)

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“…Recently, increasing effort has been devoted to reveal the relationship between food intake and skin condition, which led to the modern concept of "skin care from within" [5,13]. It has been reported that some nutrients, such as vitamin A, E, C, as well as the herbal extracts, such as pycnogenol, orange extract and grape seeds extract exhibited skin lightening effects due to their antioxidant effects [5,6,14]. In this respect, the importance of the dietary source for photoprotection has attracted a great interest.…”

Section: Discussionmentioning

confidence: 99%

Instrumental Evaluation of the Depigmenting Efficacy of an Oral Supplementation Containing Peptides and Chrysanthemum Extract for the Treatment of Melasma

Gui¹,

Kan²,

et al. 2017

Cosmetics

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Abstract:The aim of this study was to assess the efficacy of an oral supplement (CP) containing collagen peptide, soy peptide, and chrysanthemum extract in Chinese female adult volunteers with melasma. The approval of the Institutional Ethics Committee of the third affiliated hospital, Sun-Yat Sen University, was obtained before the study. A signed consent was obtained from each volunteer prior to study to enable the volunteer to appreciate the aim of the study and the consequences of her consent. Sixty-two female volunteers aged 30-60 years were included in the study, and were randomized into a treatment group or a placebo group. The skin tone of the pigmented spots was evaluated using Chromameter, and pigment density was evaluated using Mexameter before and after the treatment. Significant changes in skin tone parameters of L value and ITA • (individual typology angle) were detected in the lesion area after the treatment (P < 0.01). When compared with placebo group, the treatment group achieved significant improvement in the brightness of the pigmented spots at the 45 and 60-day time points. A significant decrease in the level of melanin was observed in the treatment group when compared with the placebo group (p < 0.01). All data demonstrated through non-invasive in vivo instrumental measurement that daily oral intake of CP had clinical efficacy of reducing melasma severity.

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Section: Discussionmentioning

confidence: 99%

Instrumental Evaluation of the Depigmenting Efficacy of an Oral Supplementation Containing Peptides and Chrysanthemum Extract for the Treatment of Melasma

Gui¹,

Kan²,

et al. 2017

Cosmetics

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“…However, if the exposure time is further extended to 15 min, it will lead to skin damage (McKenzie et al 2009). In addition, long-term exposure of skin against UV radiations leads to premature aging or photoaging, which is characterized by wrinkle formation, hyperpigmented lesions or age spots, and decrease in the integrity of the skin (Puglia et al 2014). Photoaging can be characterized by fragmentation and reduced production of collagen in the skin.…”

Section: Introductionmentioning

confidence: 99%

Ultraviolet-A triggers photoaging in model nematode Caenorhabditis elegans in a DAF-16 dependent pathway

Prasanth

Santoshram

Bhaskar

et al. 2016

AGE

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Ultraviolet radiations (UV) are the primary causative agent for skin aging (photoaging) and cancer, especially UV-A. The mode of action and the molecular mechanism behind the damages caused by UV-A is not well studied, in vivo. The current study was employed to investigate the impact of UV-A exposure using the model organism, Caenorhabditis elegans. Analysis of lifespan, healthspan, and other cognitive behaviors were done which was supported by the molecular mechanism.

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“…자외선 B (ultraviolet B, UVB)는 최근 오존층 파괴로 인한 투과가 증가되는 추세이며 [31], 따라서 UVB에 대한 피부의 노출에 의하여 피부 질환 및 광 노화 등이 증가되고 있다 [19].…”

Section: 서 론unclassified

Peptides-derived from Scales of Branchiostegus japonicus Inhibit Ultraviolet B-induced Oxidative Damage and Photo-aging in Skin Cells

오민창¹,

김기천²,

고창익³

et al. 2015

Journal of Life Science

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Collagen peptides, which are found at high concentrations in the human body, are present in animal bones and the skin of marine organisms, namely, fish scales. Collagen is the most abundant structural protein of various connective tissues in animals. Furthermore, it is widely used in biomedical material, pharmaceutical, cosmetic, food, and leather industries. Peptides extracted from scales of various fish protect against ultraviolet B (UVB)-induced skin damage and photo-aging. However, the protective effects of collagen peptides derived from the scales of Branchiostegus japonicus against UVB exposure are unclear. This study investigated the effects of peptides larger than 1 kDa (high-molecular weight peptides [HMP]) and smaller than 1 kDa (low-molecular weight peptides [LMP]), derived from extracts of B. japonicus scales, against UVB-induced skin damage and photo-aging. These peptides scavenged 1,1-diphenyl-2-picrylhydrazyl radicals in a dose-dependent manner. In UVB-exposed HaCaT human keratinocytes, LMP inhibited 8-isoprostane generation, a marker of cellular lipid peroxidation. The peptides also suppressed the UVB-induced increase in tyrosinase activity and melanin content in B16F10 mouse melanoma cells. In addition, the LMP and HMP treatment suppressed UVB-induced elastase and matrix metalloproteinase-1 activities in the HaCaT cells. These results indicate that peptides derived from B. japonicus scales have antioxidant, antiphoto-aging, and skin-whitening effects.

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Protective effect of red orange extract supplementation against UV‐induced skin damages: photoaging and solar lentigines

Abstract: Red orange extract intake can strengthen physiological antioxidant skin defenses, protecting skin from the damaging processes involved in photo-aging and leading to an improvement in skin appearance and pigmentation.

Cited by 50 publications

References 17 publications

Instrumental Evaluation of the Depigmenting Efficacy of an Oral Supplementation Containing Peptides and Chrysanthemum Extract for the Treatment of Melasma

Instrumental Evaluation of the Depigmenting Efficacy of an Oral Supplementation Containing Peptides and Chrysanthemum Extract for the Treatment of Melasma

Ultraviolet-A triggers photoaging in model nematode Caenorhabditis elegans in a DAF-16 dependent pathway

Peptides-derived from Scales of Branchiostegus japonicus Inhibit Ultraviolet B-induced Oxidative Damage and Photo-aging in Skin Cells

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