Protective effect of selenomethionine on kidney injury induced by ochratoxin A in rabbits

Zhang, Ziqiang; Sun, Yingying; Xie, Hui; Wang, Jiajia; Zhang, Xin; Shi, Zhangyu; Liu, Yumei

doi:10.1007/s11356-022-24297-7

Cited by 7 publications

(2 citation statements)

References 70 publications

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“…According to reports, OTA causes oxidative stress in human kidney-2 cells, which regulates the translocation of transcription factors such as the aryl hydrocarbon receptor (AhR) and the pregnant X receptor (PXR). By modulating cytochrome enzymes (CYP1A1 and CYP1A2), OTA activation of Ahr and PXR causes immunosuppression, renal damage, and malignancy (Zhang et al, 2022b). The first epidemics of ochratoxicosis were discovered in laying hens, broiler chickens, and turkey birds.…”

Section: Effects Of Ochratoxins On Animal Healthmentioning

confidence: 99%

Different Molds and their Toxins: As Contaminants in one Health Perspective

2023

IJAB

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Section: Effects Of Ochratoxins On Animal Healthmentioning

confidence: 99%

Different Molds and their Toxins: As Contaminants in one Health Perspective

2023

IJAB

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“…However, recent research suggests that selenium may counteract OTA's cytotoxicity and oxidative stress damage. Various studies have shown that selenium can enhance cell survival after OTA exposure, activate the antioxidant response, and reduce oxidative stress and apoptosis in OTA-induced kidney injury [85]. Both SeMet and sodium selenite have demonstrated protective effects, possible through upregulation of antioxidant enzyme expression and the downregulation of apoptosis-related factors [86].…”

Section: Antifungal Activity Of Selenium and Selenium Nanoparticlesmentioning

confidence: 99%

Efficacy of Selenium for Controlling Infectious Diseases

Gopika Vinayamohan,

Joseph,

Susan Viju

et al. 2023

Selenium and Human Health

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Selenium, an essential micronutrient for both animals and humans, has been documented to possess antimicrobial properties against a wide range of pathogenic microorganisms. One of the primary mechanisms by which selenium exerts its antimicrobial activity is through the generation of reactive oxygen species that can damage microbial cells. Besides its direct antimicrobial effects, selenium can enhance the immune response to infections, making it a potential tool in the prevention and treatment of infectious diseases. Given the growing threat of antibiotic resistance and the need for alternative therapeutic options, the antibacterial properties of selenium are of interest to the scientific community. This book chapter will summarize the current state of knowledge on the antibacterial properties of selenium, and its potential clinical applications as a therapeutic agent against infectious diseases. Further, the chapter explores the limitations and challenges associated with the use of selenium as an antibacterial agent.

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Selenomethionine alleviates Aeromonas hydrophila-induced oxidative stress and ferroptosis via the Nrf2/HO1/GPX4 pathway in grass carp

Yu,

Su,

et al. 2024

Fish & Shellfish Immunology

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Protective effect of selenomethionine on kidney injury induced by ochratoxin A in rabbits

Cited by 7 publications

References 70 publications

Different Molds and their Toxins: As Contaminants in one Health Perspective

Different Molds and their Toxins: As Contaminants in one Health Perspective

Efficacy of Selenium for Controlling Infectious Diseases

Selenomethionine alleviates Aeromonas hydrophila-induced oxidative stress and ferroptosis via the Nrf2/HO1/GPX4 pathway in grass carp

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