2015
DOI: 10.1186/s12906-015-0908-9
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Protective effect of Suxiao jiuxin pill, a traditional Chinese medicine, against acute myocardial ischemia in dogs

Abstract: BackgroundThe purpose of this study was to investigate the effect of Suxiao Jiuxin Pill (SX), a traditional Chinese medicine, on acute myocardial ischemia induced by coronary occlusion in anesthetized dogs.MethodsAcute myocardial ischemia model was established by ligating the left anterior descending artery to reduce flow by 90 %. Adult mongrel dogs were randomly divided into six groups: model, SX high dose, SX middle dose, SX low dose, Isosorbide dinitrate (ISD) and Sham groups. Adult mongrel dogs were anesth… Show more

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Cited by 24 publications
(14 citation statements)
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“…Traditional Chinese medicine receives considerable attention due to its effective effects with low-side effects, including in the field of myocardial ischemia [7,8]. For example, Suxiao jiuxin pill as a traditional Chinese medicine reveals effects against myocardial ischemia in dogs [9]. Among all these identified medicine compound, lentinan (LEN) has been proved to be an interesting medicine used in various kinds of diseases because of its biological activities, such as anticancer, antibacterial, antiviral, and antioxidant effects [10][11][12].…”
Section: Introductionmentioning
confidence: 99%
“…Traditional Chinese medicine receives considerable attention due to its effective effects with low-side effects, including in the field of myocardial ischemia [7,8]. For example, Suxiao jiuxin pill as a traditional Chinese medicine reveals effects against myocardial ischemia in dogs [9]. Among all these identified medicine compound, lentinan (LEN) has been proved to be an interesting medicine used in various kinds of diseases because of its biological activities, such as anticancer, antibacterial, antiviral, and antioxidant effects [10][11][12].…”
Section: Introductionmentioning
confidence: 99%
“…e results indicated that the statistical difference for physical activity and daily diet intake between the two groups was insignificant ( Table 1). Although Danshen and Suxiao Jiuxin have some effects on HR and BP [46,47], the statistical difference for the number of patients taking medicine between the two groups was insignificant ( Table 1, P > 0.05).…”
Section: Baseline Characteristicsmentioning
confidence: 92%
“…The Suxiao Jiuxin pill (SJP) is a traditional Chinese herbal medicine (TCM) that has a clinical application in angina pectoris with notable cardioprotective effects [1][2][3][4] . The major components of SJP include tetramethylpyrazine (TMP) and borneol (BOR).…”
Section: Introductionmentioning
confidence: 99%