Protective Effect of TOSCARE™ on Toxic Actions by Reactive Oxygen Species and Heavy Metals

Noh, Yoohun; Jeon, Byung-Ju; Lee, Seung‐Ah; Myeong, Jaeho; Kim, Ga‐Young; Lee, Jiwon; Kim, Sung‐Su; Hong, Junkee

doi:10.52361/fsbh.2021.1.e6

Cited by 1 publication

(1 citation statement)

References 15 publications

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“…Exposure to these environmental pollutants induces several adverse effects related to cardiovascular and respiratory systems when inhaled over time [14,15]. For instance, exposure to Pb may induce an increased release of reactive oxygen species (ROS), which, among many other effects, impair the normal function of the pancreatic cells and further enhances insulin resistance in the body [16,17]. Such impaired biological processes have been shown to influence blood glucose metabolism and regulation in humans [18].…”

Section: Introductionmentioning

confidence: 99%

Relationship between Metal Exposures, Dietary Macronutrient Intake, and Blood Glucose Levels of Informal Electronic Waste Recyclers in Ghana

Dawud

Takyi

Arko‐Mensah

et al. 2022

IJERPH

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While metal exposures are generally high among informal electronic waste (e-waste) recyclers, the joint effect of metals and dietary macronutrients on their metabolic health is unknown. Therefore, we investigated the relationship between metal exposures, dietary macronutrients intake, and blood glucose levels of e-waste recyclers at Agbogbloshie using dietary information (48-h recall survey), blood metals (Pb & Cd), and HbA1C levels of 151 participants (100 e-waste recyclers and 51 controls from the Accra, Ghana) in March 2017. A linear regression model was used to estimate the joint relationship between metal exposures, dietary macronutrient intake, and blood glucose levels. Except for dietary proteins, both groups had macronutrient deficiencies. Diabetes prevalence was significantly higher among controls. Saturated fat, OMEGA-3, and cholesterol intake were associated with significant increases in blood glucose levels of recyclers. In a joint model, while 1 mg of cholesterol consumed was associated with a 0.7% increase in blood glucose, 1 g/L of Pb was found to significantly increase blood glucose levels by 0.9% among recyclers. Although the dietary consumption of cholesterol and fat was not high, it is still possible that exposure to Pb and Cd may still increase the risk of diabetes among both e-waste recyclers and the general population.

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