Protective effects of a day/night dual‐antioxidant serum on skin: A randomized, regimen‐controlled study in Chinese women exposed to air pollution

Abstract

Background Chronic exposure to air pollution can negatively affect skin health. Aims To assess the efficacy of the LUMIVIVE® System (LVS), a skincare system consisting of individual day and night serums, in Chinese women exposed to air pollution. Patients/Methods In this single‐center, vehicle‐controlled study, eligible females (mean age, 49.02 years) were randomized 1:1 to treatment group (LVS plus basic moisturizer) or control group (basic moisturizer). Skin color, sebum content, barrier function, elasticity, and texture were measured at baseline and at each follow‐up visit (days 28, 56, and 84). Air pollution parameters were collected throughout the study. Results Air pollution levels, including PM2.5 and NO2, were consistently high during the study. The treatment group showed significantly higher skin color L* (p ≤ 0.0001) and lower a* values (p ≤ 0.05) at all follow‐up visits compared with the control group, indicating lower skin pigmentation and redness, respectively. Skin color L* and a* values remained unchanged over time for the control group but were significantly different at all follow‐up visits compared to baseline (p ≤ 0.0001 and p ≤ 0.05, respectively) for the treatment group. There was an increasing trend for sebum content in the control group, which was not observed in the treatment group. Both groups showed improvements over time in other skin physiology parameters. Conclusions The current analysis demonstrates the efficacy of LVS plus basic moisturizer compared with basic moisturizer alone to reduce skin pigmentation and redness, as well as to mitigate sebum production, in Chinese women exposed to air pollution.

Antioxidant Activity of Facial Wash, Moisturizer, and Serum Containing Andrographis paniculata Extract, Syzygium aromaticum Oil, and Pogostemon cablin Oil

“…Employing methods from randomized controlled trials to blinded assessments ensures the reliability of results, advancing the scientific foundation for skincare development and validating efficacy claims. 19,[31][32][33][34] This study highlights the antioxidant potential of combining Andrographis paniculata, Syzygium aromaticum, and Pogostemon cablin in anti-aging products. However, due to the variety of free © 2024 the authors.…”

“…Integrated into skincare products, such as facial wash, moisturizer, and serum, these extracts aim to counteract skin aging by acting as antioxidant. Highlighting the importance of product-based research, Liu et al, 19 demonstrated that the LUMIVIVE® System (LVS), a day and night serum duo with antioxidants and peptides, alongside a basic moisturizer, reduced pigmentation, redness, and maintained sebum levels, especially in pollution-exposed populations. This study highlights the potential of combining Andrographis paniculata, Syzygium aromaticum, and Pogostemon cablin in antiaging cosmetics, focusing on the antioxidant activity of developed skincare products such as facial wash, moisturizer, and serum.…”

Preventative effects of antioxidants on changes in sebocytes, outer root sheath cells, and Cutibacterium acnes-pretreated mice by particulate matter: No significant difference among antioxidants

“…Similarly, antioxidants from Deschampsia antartica extract and antioxidant serum were evaluated in vivo through direct skin treatment in clinical subjects. 37 , 38 These research models have proven to be robust and useful in elucidating the effects of antioxidants against various pollutants and can thus be adopted in future studies.…”