“…The most common drugs in term of treatment cardiovascular disease are nitroglycerin, nitrosorbid, nitroprusside, and nitrite, which release NO in cells and tissues during their metabolism (Münzel and Schulz, 2010; Kapelko et al, 2017; Gatzke et al, 2018; Liu et al, 2019; Lu et al, 2019; Zhao et al, 2019). However, these drugs are often unstable, non-specific, toxic, and have a number of side effects (Tardiolo et al, 2019).…”