Protective effects of electroacupuncture on polycystic ovary syndrome in rats: Down-regulating Alas2 to inhibit apoptosis, oxidative stress, and mitochondrial dysfunction in ovarian granulosa cells

Cong, Jing; Li, Mubai; Wang, Yu; Ma, Hongli; Yang, Xiaoguang; Gao, Jingshu; Wang, Long; Wu, Xiaoke

doi:10.1016/j.tice.2023.102090

Cited by 1 publication

(1 citation statement)

References 45 publications

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“…Cong et al 33 also clarified the ability of electroacupuncture to resist the effects of PCOS by inhibiting endoplasmic reticulum stress-mediated apoptosis and autophagy of ovarian granulosa cells. In addition, electroacupuncture can also improve the reproductive characteristics of PCOS rats by regulating hypothalamic neuropeptide Y and growth hormone levels, 34 regulating Alas2-mediated apoptosis and mitochondrial function, 39 and regulating kisspeptin-GnRH/LH pathway through androgen activity attenuation. 35 Chen et al 40 showed that electroacupuncture also had a certain promoting effect on ovarian function and menstrual cycle of POF mice.…”

Section: Electroacupuncturementioning

confidence: 99%

Clinical Efficacy and Experimental Research Progress on Traditional Chinese Medicine Moxibustion Therapy in Ovarian Injury

Wang,

Zhang,

Zheng

et al. 2024

Chinese medicine and natural products

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This review summarizes the clinical efficacy and experimental research of traditional Chinese medicine (TCM) moxibustion in the intervention of ovarian injury. Clinical and experimental research results have shown that as a nonpharmacological treatment method, Chinese medical moxibustion therapy is of great significance in the treatment of ovarian injuries such as diminished ovarian reserve, polycystic ovarian syndrome, premature ovarian failure, and premature ovarian insufficiency. Moxibustion, heat-sensitive moxibustion, and electroacupuncture have significant effects in improving ovarian function, overall treatment efficacy, pregnancy rate, ovulation rate, and sex hormone levels and have higher safety. Their therapeutic mechanisms have also been demonstrated. In conclusion, TCM moxibustion therapy has a significant effect in the treatment of ovarian injury, providing a new option for the treatment of the ovarian injury.

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