Protective Effects of Local Hypothermia in Vitrectomy Under Fluctuating Intraocular Pressure

Effect of 2-(6-cyano-1-hexyn-1-yl)adenosine on ocular blood flow in rabbits

“…The ocular blood flow in the posterior area of the eye in rabbits was assessed as described previously (Tamai and Toumoto, 1996;Tamai et al, 1997). Briefly, ocular blood flow (ml/min/100 g) was measured by placing the probe of a non-contact laser flowmeter (ALF21N, Advance Co. Ltd., Tokyo, Japan) over the cornea.…”

Morphological changes in the optic disc after vitrectomy and fluid–air exchange

“…This may well have prevented post-operative visual field loss in this study. Additionally, it has also been suggested that damage to the optic disc can be reduced by applying cold irrigating solutions [5,17].…”

“…There was no significant difference in intraocular pressure among any of the patient groups either pre-or post-operatively Table 2 Pre-and post-operative HRT parameters. There was no significant difference in HRT parameters among any of the patient groups pre-operatively (11)(12)(13)(14)(15)(16)(17)(18) coemulsification and posterior chamber intraocular lens implantation were involved in all of the patients with the exception of two that had already undergone cataract surgery elsewhere. Following a pars plana vitrectomy, the adherent posterior cortical vitreous was engaged using a vitreous cutter with active aspiration in every case but one, in which PVD was already apparent pre-operatively (Table 2).…”

Hypothermia Protects Cultured Human Retinal Pigment Epithelial Cells against Trypan Blue Toxicity

“…Although it is not possible to cool and maintain eyes at 4°C, surgery with the dye, even at low concentrations, might have to be performed with hypothermic irrigation solutions to minimize the toxic effects of TB. In addition, local hypothermia during vitrectomy inhibits the breakdown of the blood-aqueous barrier in the early postoperative period and protects the retina against ischemic damage [22, 23]. …”