Protective effects of Shensuitongzhi formula on intervertebral disc degeneration via downregulation NF-κB signaling pathway and inflammatory response
Qinwen Ge,
Xu Wang,
Qinghe Zeng
et al.
Abstract:Low back pain (LBP) is a common orthopedic disease over the world. Lumbar intervertebral disc degeneration (IDD) is been regarded as an important cause of LBP. Shensuitongzhi formula (SSTZF) is a drug used in clinical treatment for orthopedic diseases. It has been found that SSTZF can have a good treatment for IDD. But the exact mechanism has not been clarified. The results showed that SSTZF protects against LSI-induced degeneration of cartilage endplates and intervertebral discs. Meanwhile, SSTZF treatment dr… Show more
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