Protective Influence of Gamma Rays and Electron-Beam Irradiation with a Commercial Toxin Binder on Toxic Effects of Aflatoxin B1 in Japanese Quails

Abstract

Background: This cross sectional study was conducted to evaluate the effect of &gamma-rays and electron-beam irradiation with a commercial toxin binder-milbond-TX on the performance, feed components, and meat quality of Japanese quails challenged with aflatoxin B1. Methods: Overall, 168 One-d-old chicks (Japanese quails) were allocated to eight treatments with three replicates based on a completely randomized design in a 2×4 factorial arrangement. Two levels of aflatoxin (Zero and 2 ppm) were considered as the essential factor. The secondary factor was involved in four levels (Control, 27 k Gy doses of &gamma-rays, electron-beam irradiation, and 0.3% commercial toxin binder-milbond-TX). Results: In vitro condition showed that experiment diets do not have any effect on meat quality and feed components such as malondialdehyde, protein, fat, ash, and the dry matter. However, the highest and the lowest levels of feed intake and body weight gain were observed in the 7th treatment (2-ppm aflatoxin B1 + electron-beam irradiation) and the 2nd treatment (2-ppm aflatoxin B1 alone), respectively in 1-15 and 29-42 days (P&le0.05). In addition, the highest liver weight (1.73), spleen (0.57) and bursa (0.18) were seen in the second treatment (2 ppm aflatoxin B1) alone (P&le0.05) at the age of 42 days. Conclusion: &gamma-rays and electron-beam irradiation plus commercial toxin binder-milbond-TX can be used for aflatoxin B1 absorption in poultry diets.

Accelerated Electron Ionization-Induced Changes in the Myenteric Plexus of the Rat Stomach

“…Electron radiation has specific physical mechanisms of penetration and interaction with matter, different from those of electromagnetic ionizing radiation. Depending on their energy, flows of accelerated electrons penetrate different depths in tissues and phantom models [ 6 , 7 , 8 ]. In this sense, they provoke specific ionization-induced effects in targeted tissues, leading to disturbances in their cellular functions [ 9 ], membrane permeability, enzyme reactions [ 10 ], etc.…”

Effects of Electron Radiation on Serotonin Signaling and Reactivity of Rat Gastric Smooth Muscle

“…Accelerated electron beams penetrate at different depths into tissues and phantoms, depending on their energy [ 13 ]. Even though most electron energy is absorbed superficially, electron beams can treat tumors at a 5 cm depth [ 14 ] and even up to a depth of 4 inches [ 15 ]. Entering the body, accelerated electrons provoke ionizing-induced effects on target tissues, and these effects could cause functional and/or structural changes in the 5-HT receptor [ 16 , 17 ].…”