Protective influence of vitamin E on the antioxidant defence system in the whole blood and liver of normal and alloxan-induced diabetic rats

Olanlokun, J. O.

doi:10.1007/s12291-008-0015-5

Cited by 6 publications

(2 citation statements)

References 26 publications

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“…In liver homogenates of preventively AAEO treated broilers and then infected (group D 2 ) was observed a significant increase of GSH content, decrease of LPx content, induction of GSHPx activity and inhibition of POD, SOD, GR and XOD activity in comparison with the control group A. This finding is in line with data published by Olanlokun (2008). Observed changes show positive preventive effects of applied AAEO.…”

Section: Enzymatic Activity In Liver Homogenatessupporting

confidence: 90%

Effect of Artemisia absinthium essential oil on antioxidative systems of broiler's liver

Kostadinović¹,

Čabarkapa²,

Lević³

et al. 2014

Food & Feed Res

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The effect of Artemisia absinthium essential oil (AAEO) on enzymatic activity of superoxide-dismutase (SOD), glutathione-peroxidase (GSHPx), glutathione-reductase (GR), peroxidase (POD), xantine-oxidase (XOD) and non-enzymatic (content of lipid peroxides (LPx) and gluthathione (GSH)) antioxidative status of broilers infected with mixture of oocysts of Eimeria tenella, Eimeria mitis and Eimeria necatrix in comparison to coccidiostat salinomycin was investigated. The in vivo investigation were carried out on 120 Arbor acres broilers of both sexes. Broilers were randomly distributed into four groups. Group A was uninfected and untreated; group B was infected and was kept untreated; group C preventively received coccidiostatic salinomycin in quantity of 60 mg/kg of feed and was inoculated with coccidia species at 21 st day-of-age and group D received in feed AAEO in quantity of 3 g/kg and was infected with Eimeria oocysts at 21 st day-of-age. Livers were collected for the subsequent evaluation of antioxidative status. It was concluded that AAEO added in feed for broilers prevented the development of coccidia oocysts and therefore it can be used as prophylactic feed additive.

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Section: Enzymatic Activity In Liver Homogenatessupporting

confidence: 90%

Effect of Artemisia absinthium essential oil on antioxidative systems of broiler's liver

Kostadinović¹,

Čabarkapa²,

Lević³

et al. 2014

Food & Feed Res

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“…hence, SINGh et al (2011) reported that an increase in catalytic activity of superoxide-dismutase is expected as part of the system defense. KOSTADINOVIĆ et al (2015) showed that addition of Artemisa absinthium to broiler diet led to higher SOD activity in hemolysed blood and liver homogenates, which was also in agreement with the results reported by OLANLOKUN (2008). On the other hand, KOSTADINOVIĆ et al (2015) reported that GShPx levels were not altered by Artemisia absinthium supplementation, which is not in accordance with the results obtained in this study.…”

Section: Discussionsupporting

confidence: 75%

Potential of wormwood (Artemisia absinthium) as a feed supplement in rabbit diet: effect on controlling rabbit coccidiosis, antioxidative systems and growth performance

Popović¹,

Kostadinović²,

Puvača³

et al. 2017

Vet. arhiv

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Protective effects of vitamins (C and E) and melatonin co-administration on hematological and hepatic functions and oxidative stress in alloxan-induced diabetic rats

et al. 2014

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The present study aimed to investigate the potential effects of vitamins (C and E)/melatonin co-administration on the hematologic and hepatic functions and oxidative stress in alloxan-induced diabetic rats. The intraperitoneal injection of alloxan (120 mg/kg b.w. for 2 days) induced a significant increase of blood glucose levels (hyperglycemia) associated with serious hematologic disorders (P < 0.01) evidenced by the decrease in the levels of red blood cell count (RBC) (-18%), hematocrit (Ht) (-18%), hemoglobin content (Hb) (-36%), mean corpuscular hemoglobin (MCH) (-17%), and mean corpuscular hemoglobin concentration (MCHC) (-16%). The activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and the plasmatic levels of total cholesterol and triglyceride contents of diabetic rats were, however, noted to undergo significant increases by 42% (P < 0.01), 134% (P < 0.001), 27.5% (P < 0.01), 147% (P < 0.001), and 67% (P < 0.01), respectively, as compared to the control animals. Furthermore, a significant increase in malondialdehyde (MDA) content and a significant decrease in superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) activities were observed in the plasma and hepatic tissues of diabetic rats when compared to the controls. Interestingly, the treatment with vitamins (C, E) in combination with melatonin was noted to reduce the plasma levels of glucose, lower the MDA levels, and restore the hematologic parameters and biochemical and antioxidant levels of diabetic rats back to normal values, alleviating diabetes metabolic disorders in rats.

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Protective influence of vitamin E on the antioxidant defence system in the whole blood and liver of normal and alloxan-induced diabetic rats

Cited by 6 publications

References 26 publications

Effect of Artemisia absinthium essential oil on antioxidative systems of broiler's liver

Effect of Artemisia absinthium essential oil on antioxidative systems of broiler's liver

Potential of wormwood (Artemisia absinthium) as a feed supplement in rabbit diet: effect on controlling rabbit coccidiosis, antioxidative systems and growth performance

Protective effects of vitamins (C and E) and melatonin co-administration on hematological and hepatic functions and oxidative stress in alloxan-induced diabetic rats

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