Protective Role of Wheat Germ Oil against Hyperglycemia and Hyperlipidemia in Streptozotocin Induced Diabetic Rats

Merghani, Basma H.; Awadin, Walaa; Elseady, Yousef; Abu-Heakal, S.A. Nabil

doi:10.3923/ajava.2015.852.864

Cited by 10 publications

(2 citation statements)

References 37 publications

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“…and 500 mg/kgb.wt.) to STZ-induced diabetic male Sprague Dawely rats and reduced contents of liver MDA, percentage of HbA1c, atherogenic index and serum lipid profile while high density lipoproteins concentration was significantly elevated [43].…”

Section: Diabetesmentioning

confidence: 85%

Wheat compounds – A comprehensive review

Mughal¹

2019

Integr Food Nutr Metab

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Wheat bran is recognized as one of the prominent and economically cheap sources of dietary fibers, minerals, vitamins, bioactive compounds and is also used to prepare many food-based commodities. Wheat is considered unique among all cereal crops because it has a special protein called gluten that is produced with the rheological features needed to make leavened bread during the process of dough production. Consumption of wheat bran improves the health and prevents some diseases including colon cancer, cardiovascular diseases. The current review article discusses the importance of wheat bran, its composition, extraction methods and its health benefits.

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Section: Diabetesmentioning

confidence: 85%

Wheat compounds – A comprehensive review

Mughal¹

2019

Integr Food Nutr Metab

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“…Rocket, E. sativa is considered an important leafy vegetable crop that is high in antioxidant molecules, and its seeds contain oil up to 25-35% [11]. Wheat has been called the staff of life, and people who have many health concerns have used wheat germ oil [57]. Wheat germ oil represents about 10-15% of the whole wheat germ, which is reported to be one of the potential resources for beneficial molecules [21].…”

Section: Growth Performance and Feed Utilizationmentioning

confidence: 99%

Effects of Rocket Seed Oil, Wheat Germ Oil, and Their Mixture on Growth Performance, Feed Utilization, Digestibility, Redox Status, and Meat Fatty Acid Profile of Growing Rabbits

et al. 2021

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Vegetable oils are a source of natural antioxidants, including tocopherols, sterols, phenolic compounds, coenzymes, and polyunsaturated fatty acids that provide nutritional value, organoleptic properties, and significantly delay or prevent lipid oxidation. Eighty-four V-line rabbits at 5 weeks of age with an initial body weight (BW) of 535.60 ± 13.48 g were assigned randomly to four experimental groups (seven replicates in each group with three rabbits each). The first group served as a control and received 0.3 mL/kg BW of distilled water (CON), while the second and third groups received 0.3 mL/kg BW of rocket seed oil (RSO) and wheat germ oil (WGO), respectively. The fourth group received a mixture of oils consisting of 0.15 mL of RSO and 0.15 mL of WGO/kg BW (MOs). The experiment lasted 7 weeks. The study investigated the effects of RSO, WGO, and their mixture on growth performance, feed utilization, antioxidant status, and immune response of growing rabbits. The results indicated that the rabbits that were administered orally with RSO and WGO or their mixture had higher (p ≤ 0.05) final BW, weight gain, and average daily gain when compared to the control group. In addition, the feed conversion ratio improved significantly with RSO, WGO, and MOs treatments. Different oil treatments improved nutrient digestibility, nutritive value, and nitrogen balance. Moreover, the rabbits that received RSO, WGO, and their mixture had an improvement the meat fatty acid composition compared to the control rabbits. Oral administration of RSO, WGO, and their mixture significantly improved serum protein fractions, decreased blood urea nitrogen, and had a positive effect on serum total lipids, HDL-c, and LDL-c. Furthermore, the treatments of RSO, WGO, and MOs had a significant improvement in the antioxidative status and immune response.

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Beneficial effects of curcumin in the diabetic rat ovary: a stereological and biochemical study

Tüfekci

Kaplan

2022

Histochem Cell Biol

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Study investigated the effects of curcumin treatment on diabetic ovaries at different periods of the disease. Fifty-six female Wistar albino rats (250-300 g) aged 12 weeks were divided into seven groups. No treatment was applied to the control group. The sham group was given 5 mL/kg of corn oil, and the curcumin group 30 mg/kg curcumin. In the DM groups, diabetes was induced by a single intraperitoneal dose of 50 mg/kg streptozotocin (STZ). The DM-treated groups received 30 mg/kg curcumin after either seven days (DC1 group), or 21 days (DC2 group), or simultaneously with STZ injection (DC3 group). Numbers of follicles in the ovaries were estimated using stereological method. FSH, LH, and SOD levels and CAT activity were measured in serum specimens. Follicle numbers and volumes of corpus luteum, blood vessel and cortex volumes, gonadosomatic index, and FSH and SOD levels all decreased signi cantly in diabetic ovaries, while relative weight loss, connective tissue volume, and CAT activity increased (p < 0.01). Curcumin treatment had a protective effect on the number of primordial follicles in the DC2 group and on antral follicle numbers in the DC3 group. Curcumin also exhibited positive effects on CAT activity and SOD levels, blood glucose levels, and corpus luteum, connective tissue and blood vessel volumes in the DC2 and DC3 groups. Curcumin also ameliorated FSH levels in the DC1 and DC3 groups (p < 0.01). Curcumin exhibits protective effects on ovarian structures and folliculogenesis, especially when used concurrently with the development of diabetes or in later stages of the disease.

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Protective Role of Wheat Germ Oil against Hyperglycemia and Hyperlipidemia in Streptozotocin Induced Diabetic Rats

Cited by 10 publications

References 37 publications

Wheat compounds – A comprehensive review

Wheat compounds – A comprehensive review

Effects of Rocket Seed Oil, Wheat Germ Oil, and Their Mixture on Growth Performance, Feed Utilization, Digestibility, Redox Status, and Meat Fatty Acid Profile of Growing Rabbits

Beneficial effects of curcumin in the diabetic rat ovary: a stereological and biochemical study

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