Protein Analysis-on-Chip Systems in Foodomics

Abstract

Protein compositional data can address nutritional, packaging, origin/authenticity, processing history, safety and other quality questions. Such data has been time-consuming and expensive to generate until recently but “protein analysis on a chip” systems are now available that can analyze a complex food sample in a few minutes and do not require great protein analytical expertise. We review some of the main new approaches with examples of their application and discuss their advantages and disadvantages.

Recent advances in the application of capillary electromigration methods for food analysis and Foodomics

“…Analysis of flavonoids in foods 2011 [4] Food analysis by CE 2011 [5] Sample stacking in CE 2011 [6] Applications of MEKC 2011 [7] Advanced analysis of nutraceuticals 2011 [8] Analysis of transgenic foods 2011 [9] Authentication and traceability by CE 2011 [10] Food analysis and Foodomics 2012 [3] Foodomics 2012 [11,12] Protein-chip-systems in Foodomics 2012 [13] Food analysis on microchip electrophoresis 2012 [14,15] Analysis of wine and its precursors by CE 2012 [16] Mycotoxin detection via CE and lateral flow technology 2012 [17] CE with C 4 D 2012 [18] Analysis of natural products by CE 2012 [19] Enantioseparations by CE 2012 [20] Analysis of antibiotics by CE and CEC 2012 [21] Analysis of amino acids by MEKC 2012 [22] Developments in coupled SPE-CE 2012 [23] Proteomics and peptidomics for food bioactive peptides 2012 [24] Recent applications of CE-MS 2013 [25] CE-MS for metabolomics 2013 [26] food science and technology including the analysis of amino acids; biogenic, heterocyclic, and other hazardous amines; peptides and proteins; phenols, polyphenols, and pigments; carbohydrates, DNA; vitamins; small organic and inorganic ions; toxins, contaminants, pesticides and residues; chiral compounds; and also important compounds to investigate food interactions and food processing. An overview of the last developments and applications of microchip CE to food analysis is provided, as well as the recent results obtained by CE-MS in Foodomics applications.…”

“…Also in the mentioned period, several reviews have been published focusing on the application of CE to the analysis of transgenic foods , nutraceuticals , wine , natural products , as well as other food issues including authentication and traceability of foods from animal origin . Besides, new results from the application of CE in the field of Foodomics have been also recently reviewed .…”

System Biological Research on Food Quality for Personalised Nutrition and Health Using Foodomics Techniques: A Review

“…The recently developed lab-on-a-chip system (or Micro Total Analysis System) assembles all the protein extraction, separation, and identification processes on one microfluidic chip. In this way, the efficiency of the proteomics analysis is greatly increased by reduced sample consumption, analysis time, and cost (Nazzaro et al,. 2012).…”

Foodomics in microbiological investigations

“…The emerged foodomic approaches have been used to study the food domains through the application of advanced omics technologies to improve consumer's well-being, health, and confidence [5]. Foodomics involves the use of multiple tools to deal with the different applications in the field of food, such as genomics, transcriptomics, proteomics, and metabolomics ( Figure 1) [6][7][8].…”