Protein expression information of prostate infection based on data mining

Abula, Asimujiang; Shao, Weimin; Tusong, Hamulati; Wang, Feng; Yasheng, Anniwaer; Wang, Yue; Wang, Yujie

doi:10.1016/j.jiph.2019.07.019

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2024

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“…The nearest attempt of SCP to clinical samples was when Zhu et al analysed single circulatory tumour cell (CTC) in immunodensity-enriched human blood sample using nanoPOTS [41]. Therein, the authors have identified 3 prostate-cancer-specific biomarkers (KRT8, KRT18, and HSPD1) [98] which has differential expression in white blood cells; though, the authors mentioned that higher sensitivity methods are needed in the future to increase proteome coverage.…”

Section: F I G U R Ementioning

confidence: 99%

Single‐cell proteomics by mass spectrometry: Advances and implications in cancer research

Tan,

Low,

Lee

et al. 2024

Proteomics

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Cancer harbours extensive proteomic heterogeneity. Inspired by the prior success of single‐cell RNA sequencing (scRNA‐seq) in characterizing minute transcriptomics heterogeneity in cancer, researchers are now actively searching for information regarding the proteomics counterpart. Therefore recently, single‐cell proteomics by mass spectrometry (SCP) has rapidly developed into state‐of‐the‐art technology to cater the need. This review aims to summarize application of SCP in cancer research, while revealing current development progress of SCP technology. The review also aims to contribute ideas into research gaps and future directions, ultimately promoting the application of SCP in cancer research.

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Section: F I G U R Ementioning

confidence: 99%