Protein hydration and the huge electrostriction

Danielewicz-Ferchmin, I.; Banachowicz, Ewa; Ferchmin, A. R.

doi:10.1016/s0301-4622(03)00188-1

Cited by 24 publications

(28 citation statements)

References 13 publications

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“…As discussed in more detail elsewhere, [25] in this region small varia- Figure 3. Pairs of isotherms of water in the shells of two exemplary proteins.…”

Section: What Happens To the Hydration Shells Of Proteins Inmentioning

confidence: 74%

“…There is some literature [14,31,36] which is concerned with the problem of water properties in the hydration shell of lysozyme, following the seminal paper by Svergun et al [17] . The question of how these properties are related to the conditions at the N-D equilibrium, in these papers has not been addressed.…”

Section: Summary and Discussionmentioning

confidence: 99%

“…The permittivity e = eA C H T U N G T R E N N U N G (s,P,T) has been taken from refs. [15,16,25]. Since the actual dependence of the volume V = V(P) on the local electrostriction pressure P is not available, the isotherms V = V(P) of H 2 O under external pressure P in the absence of a field [26] are applied instead.…”

Section: Rigorous Equation Of State Of H 2 O Expressed In Terms Of Tmentioning

confidence: 99%

“…Reorientation of the H 2 O dipoles. [13,14] The strength of the local field is % 10 9 V m À1 and for such field values the water permittivity is e < 35. [15,16] [a] Prof. A. R. ) are found for six different experimental lines of the N-D transition found in the literature.…”

Section: Introductionmentioning

confidence: 99%

“…[18,19] Equation (4) shows a more explicit form of the equation; the solution of which leads to a relation between the mass density within the hydration shell and the surface charge density s. Knowing these values, one establishes a link between hydration shell characteristics [mass density (higher than that of the bulk water)] and protein properties (surface charge density). [14] We shall look for possible correlations between the properties of hydration water and the equilibrium line of proteins at the N-D transition (at temperature T t and external pressure P t , where t stands for transition). What happens to water in such conditions?…”

Section: Introductionmentioning

confidence: 99%

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Properties of Hydration Shells of Protein Molecules at their Pressure‐ and Temperature‐Induced Native‐Denatured Transition

Danielewicz-Ferchmin¹,

Banachowicz²,

Ferchmin³

2006

ChemPhysChem

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Properties of water at the surface of biomolecules are important for their conformational stability. The behaviour of hydrating water at protein transition (t) pressures P(t) and temperatures T(t) , with the points (P(t),T(t) ) lying in the Native-Denatured (N-D) transition line, is studied. Hydration shells at the hydrophilic regions of protein molecules with surface charge density sigma are investigated with the help of the equation of state of water in an open system. The local values of sigma rather close to each other (sigma(D) approximately 0.3 C m(-2)) are found for six different experimental lines of the N-D transition found in the literature. The values sigma(D) correspond to the crossings of the total pressure (P(t)+Pi) vs sigma isotherms at different T(t) (Pi-electrostriction pressure). The pressures P(t) and temperatures T(t) appear to be related with some selected sites at the surfaces of the protein molecules.

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“…As discussed in more detail elsewhere, [25] in this region small varia- Figure 3. Pairs of isotherms of water in the shells of two exemplary proteins.…”

Section: What Happens To the Hydration Shells Of Proteins Inmentioning

confidence: 74%

Section: Summary and Discussionmentioning

confidence: 99%

Section: Rigorous Equation Of State Of H 2 O Expressed In Terms Of Tmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Properties of Hydration Shells of Protein Molecules at their Pressure‐ and Temperature‐Induced Native‐Denatured Transition

Danielewicz-Ferchmin¹,

Banachowicz²,

Ferchmin³

2006

ChemPhysChem

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Applications of Solutions of Ions

Marcus

2015

Ions in Solution and Their Solvation

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Water response to intense electric fields: A molecular dynamics study

Marracino

Liberti

D’Inzeo

et al. 2015

Bioelectromagnetics

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This paper investigated polarization properties of water molecules in close proximity to an ionic charge in the presence of external electric fields by using an approach based on simulations at the atomic level. We chose sodium and chloride ions in water as examples of dilute ionic solutions and used molecular dynamics simulations to systematically investigate the influence of an external static electric field on structural, dipolar, and polarization properties of water near charged ions. Results showed that a threshold electric field higher than 10(8) V/m is needed to affect water polarization and increase mean dipole moment of water molecules close to the ion. A similar threshold holds for water permittivity profiles, although a field 10× higher is needed to ensure that water permittivity is almost constant independently of the position close to the ion. Electric fields of such intensities can greatly enhance polarizability of water in hydration shells around ions.

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Protein hydration and the huge electrostriction

Cited by 24 publications

References 13 publications

Properties of Hydration Shells of Protein Molecules at their Pressure‐ and Temperature‐Induced Native‐Denatured Transition

Properties of Hydration Shells of Protein Molecules at their Pressure‐ and Temperature‐Induced Native‐Denatured Transition

Applications of Solutions of Ions

Water response to intense electric fields: A molecular dynamics study

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