Protein intake and the use of levodopa in patients with Parkinson's disease

Fracasso, Bianca de Moraes; Morais, Maite Barcelos; Gomez, Rosane; Hilbig, Arlete; Rabito, Estela Iraci

doi:10.4067/s0717-75182013000200001

Cited by 3 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another relevant aspect about dietetic protein is that the amino acids from animal proteins and the levodopa drug compete for the same active transport mechanism in the gastrointestinal tract and blood-brain barrier, thus causing decreased absorption of the drug and affect its therapeutic action 27 .…”

Section: Discussionmentioning

confidence: 99%

Nutritional status and food consumption of patients with Parkinson disease

Fernandez

Campos

Santos³

2021

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

Background: Parkinson's disease (PD) is a neurodegenerative disease that affects food intake as the disease progresses. The assessment of nutritional status is essential to identify early nutritional deficits. Objective: To investigate the nutritional status and food intake of patients diagnosed with PD. Methods: This was a descriptive, cross-sectional, and quantitative study. A structured questionnaire with restricted questions was applied to identify the sociodemographic profile and anthropometric measurements were taken. To evaluate the disease stage, the modified Hoehn & Yahr scale was used. Food intake was evaluated using the Food Frequency Questionnaire (FFQ). The acquired information was organized in the Microsoft Office Excel 2010 program and statistical analysis was performed using the BioEstat 5.3 program. Results: The research was carried out with 40 patients; the majority was male (60%), over 60 years old (52.5%), single (55%), with a high school degree (42.5%), retirees (80%), and receiving one minimum salary (42.5%). Most were classified with eutrophic (42.5%) and overweight (42.5%). About food consumption, the most common foods were banana (60%), fish (52.5%), acerola (45%), and orange (32%). Among the high-risk foods, red meat (82.5%), fried foods (30%), heavy cream (25%), and filled sandwich cookies (25%) were the most common. Conclusions: Most patients had a high consumption of red meat and processed foods, with relevant consumption of some fruits and low consumption of grains and oilseeds. The disease stage was not associated with nutritional status.

show abstract

Section: Discussionmentioning

confidence: 99%

Nutritional status and food consumption of patients with Parkinson disease

Fernandez

Campos

Santos³

2021

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

Nutritional status in patients with Parkinson's disease at a third-level hospital in Northeastern Mexico

López-Botello

González-Peña

Berrún-Castañón

et al. 2017

Medicina Universitaria

View full text Add to dashboard Cite

Avaliação nutricional e o uso da levodopa com refeições proteicas em pacientes com doença de Parkinson do município de Macaé, Rio de Janeiro

Carmo

Ferreira

2016

Rev. bras. geriatr. gerontol.

View full text Add to dashboard Cite

Parkinson's disease (PD) is characterized by a reduction in dopamine in the central nervous system. It has a gradual progression, and is mainly known for causing tremors and difficulty in performing movements. Studies have shown that there is a significant change in the nutritional status of patients with PD. The main medication used in the treatment of patients is levodopa, and its use, without respecting the minimum intervals of 30 minutes before or one hour after meals, may diminish the pharmacological effect of the drug because of drug-nutrient interactions. The present study aimed to identify PD patients at nutritional and protein consumption risk associated with the use of levodopa in the city of Macaé. A cross-sectional quantitative and descriptive study was performed. The instruments used were the Mini Nutritional Assessment (MNA) and an estimated 3-day dietary record. The analysis was descriptive. To form the sample population a survey was performed of patients diagnosed with PD in two Department of Health programs and from the Parkinson's Association of Macaé. A total of 40 individuals were evaluated, of whom 57.5% were male. Of these, 62.5% presented a risk of malnutrition or MNA defined malnutrition, with nutritional deficit. The protein intake of the study population was 1.4 g/kg/day. The highest protein intake was during the day, including the meals between breakfast and the afternoon snack. A total of 74.7% of total protein was consumed by the population during this period. Overall, 75.0% of the elderly persons consumed their medications containing levodopa simultaneously with meals or did not follow the interval recommended by ANVISA. The study found that the total daily intake of most individuals was hyper-proteic, with proteic content being poorly distributed among meals throughout the day, and that they did not follow the recommended levodopa interval.

show abstract

Protein intake and the use of levodopa in patients with Parkinson's disease

Cited by 3 publications

References 23 publications

Nutritional status and food consumption of patients with Parkinson disease

Nutritional status and food consumption of patients with Parkinson disease

Nutritional status in patients with Parkinson's disease at a third-level hospital in Northeastern Mexico

Avaliação nutricional e o uso da levodopa com refeições proteicas em pacientes com doença de Parkinson do município de Macaé, Rio de Janeiro

Contact Info

Product

Resources

About