2023
DOI: 10.1002/biof.2032
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Protein kinase CK2: An emerging regulator of cellular metabolism

Huilin Deng,
Xinrui Rao,
Sijia Zhang
et al.

Abstract: The protein kinase casein kinase 2 (CK2) exerts its influence on the metabolism of three major cellular substances by phosphorylating essential protein molecules involved in various cellular metabolic pathways. These substances include hormones, especially insulin, rate‐limiting enzymes, transcription factors of key genes, and cytokines. This regulatory role of CK2 is closely tied to important cellular processes such as cell proliferation and apoptosis. Additionally, tumor cells undergo metabolic reprogramming… Show more

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