Protein–protein interactions in solutions of monoclonal antibodies probed by the dependence of the high-frequency viscosity on temperature and concentration

Abstract

Using a quartz crystal microbalance with dissipation monitoring (QCM-D), the complex high-frequency viscosity, η ̃ = ηʹ - iηʹʹ , of concentrated solutions of a monoclonal antibody (mAb) was studied...