Protein Recognition in Biology

Abstract

Protein recognition is pervasive in living systems. Interactions of proteins with each other and with other biomolecules occur in crowded and dynamic environments, ultimately leading to the multimolecular assemblies and networks that are recurrent components underpinning the molecular mechanisms of health and disease. Appreciating the nature and environment of protein interactions can help identify opportunities for molecular sensing in biological systems and guide the conditions needed for biomolecular sensing using biosensors and biochips.