1943
DOI: 10.1097/00000441-194306000-00035
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PROTEINS, AMINO ACIDS AND PEPTIDES as Ions and Dipolar Ions

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Cited by 475 publications
(143 citation statements)
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“…This would give rise to an electrostatic attraction for anions, and the protein is known to bind anions, including chloride (Stellwagen & Babul, 1975;Taborsky & McCollum, 1979;Osherhoff et al, 1980). Electrostatic interactions would release electrostricted water, which would cause a net rise in volume (Cohn et al, 1934;Cohn & Edsall, 1943). A V is negative, however, so if release of electrostricted water occurs, its effect is masked by another.…”
Section: Resultsmentioning
confidence: 99%
“…This would give rise to an electrostatic attraction for anions, and the protein is known to bind anions, including chloride (Stellwagen & Babul, 1975;Taborsky & McCollum, 1979;Osherhoff et al, 1980). Electrostatic interactions would release electrostricted water, which would cause a net rise in volume (Cohn et al, 1934;Cohn & Edsall, 1943). A V is negative, however, so if release of electrostricted water occurs, its effect is masked by another.…”
Section: Resultsmentioning
confidence: 99%
“…The results of all determinations are presented in Table 1. c Determined by using the formula M ϭ 6 Nas/(1 Ϫ vq) (30), where is solvent viscosity, N is Avogadro's number, a is Stokes radius, s is sedimentation coefficient, q is solvent density, and v is partial specific volume (0.73 ml/g) calculated from amino acid composition (10).…”
Section: Discussionmentioning
confidence: 99%
“…The data were analyzed globally by the program NONLIN (nonlinear least squares analysis of sedimentation equilibrium data) of Johnson et al (18). Using the program SEQSEE (19), the partial specific volumes of LSAAN and LVAAN were calculated to be 0.71 and 0.73 mg/mL, respectively (20). The density of the solution was calculated to be 1.004 g/mL.…”
Section: Methodsmentioning
confidence: 99%